Compare Imitrex vs. ergotamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Imitrex (Sumatriptan)

Prescription only

Ergomar (ergotamine)

Prescription only
Treats migraine headaches.

Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.

3.9/ 5 average rating with 31 reviewsforImitrex
Treats migraine headaches.

Ergomar (ergotamine) has more side effects than other medicines used to treat migraines.

Upsides
  • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
  • A combination of forms can be used if symptoms do not improve.
  • The nasal spray and injectable forms work very quickly.
  • It's generally safe to use if you are pregnant.
  • Comes in a generic form, so it can be pretty cheap.
  • Ergomar (ergotamine) works better than other medicines if your migraines last more than 2 days or if you have more frequent migraines.
Downsides
  • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
  • Does not prevent migraine headaches; it only treats them once they start.
  • Must wait 1 hour before using second injection.
  • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
  • Need to have your blood pressure checked often, especially if you're pregnant.
  • Harmful to the fetus so avoid if you're pregnant or think you may be pregnant.
  • Doesn't prevent migraines from happening. It can only relieve them.
  • Excessive use can be dangerous and result in rebound headaches. Talk to your doctor if your headaches are worse and occurring more frequently.
  • May not be right for you if you have high blood pressure or had a heart attack.
Used for
Dosage forms
  • Pill
  • Injection
  • Nasal spray
  • Dissolving pill
Price
No pricing information available
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Reviews
31 reviews so far
74%
saidit'sworth it
68%
saiditworked well
19%
saidit'sa big hassle

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Side effects
6possible side effects
  • Pain and other pressure sensations
    6%
  • Atypical sensations
    5%
  • Paresthesia (all types)
    3%
  • Sensation warm/cold
    3%
  • Pain - location specified
    2%
  • Malaise/fatigue
    2%
See more detailed side effects
The Ergomar (ergotamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Tightening of blood vessels (myocardial angina, ischemia, or infarction)
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    • Smoking
  • Stroke
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    • Smoking
  • Stomach bleeding
  • Serotonin syndrome
    • Patients taking SSRIs and SNRIs
  • High blood pressure
    • History of high blood pressure
  • Seizures
    • History of seizures
See more detailed risks and warnings
  • Drug interactions
    • Macrolide antibiotics
    • Protease inhibitors
  • Lowered blood flow
    • Taking Ergomar (ergotamine) more than the recommended amount daily or weekly
  • Dependency and withdrawal
    • Taking Ergomar (ergotamine) regularly for months
See more detailed risks and warnings