Compare Imitrex vs. Relpax

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Imitrex
(sumatriptan)

Relpax
(eletriptan)

Treats migraine headaches. Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.Treats migraine headaches. Relpax (eletriptan) is a first choice medicine to treat migraines, but it can be expensive.
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Coupons for Imitrex
Best available price for 9 (9 tablets of 100mg) dose packs of sumatriptan
Coupons for Relpax
Best available price for 2 (40mg) tablets of relpax
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.29Imitrex
Reviews for Imitrex
74%
of people (All ages) say Imitrex is worth it
68%
say it works well
19%
say it's a big hassle
Have you used Imitrex (sumatriptan)?
Worth itNot sureNot worth it

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Have you used Relpax (eletriptan)?
Worth itNot sureNot worth it
Side effects
ImitrexRelpax
  • Pain and other pressure sensations 2%
  • Atypical sensations 1%
  • Paresthesia (all types) 1%
  • Sensation warm/cold 1%
  • Pain - location specified 1%
  • Malaise/fatigue 2%
  • Chest - pain/tightness/pressure and/or heaviness 1%
  • Neck/throat/jaw - pain/ tightness/pressure 2%
  • Other - pressure/tightness/ heaviness 1%
  • Vertigo 2%
More Imitrex side effects »
  • Headache 1%
  • Weakness 1%
  • Tingling or prickling sensation 1%
  • Indigestion 1%
  • Abdominal issues 1%
More Relpax side effects »
How it works
ImitrexRelpax
Imitrex (Sumatriptan) is a triptan medication that treats migraine headaches. It releases serotonin, which lowers the inflammation that causes headaches.Relpax (eletriptan) is a triptan. Migraine headaches happen when blood vessels are too open and allow too much blood to the brain. Relpax (eletriptan) tightens the blood vessels, which relieves the pain.
Type of medication
ImitrexRelpax
Prescription onlyPrescription only
Available as
ImitrexRelpax
  • Pill
  • Injection
  • Nasal spray
  • Pill
Used for
ImitrexRelpax
Risk factors for serious side effects
ImitrexRelpax
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Being overweight or obese
Detailed Imitrex (sumatriptan) risks & warnings »
  • Heart rhythm problems
  • History of chest pain
  • Uncontrolled high blood pressure
  • History of a stroke
  • Using Relpax (eletriptan) for more than 10 days a month
Detailed Relpax (eletriptan) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Sleep
ImitrexRelpax
  • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
No sleep related info.
Upsides and benefits
ImitrexRelpax
  • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
  • A combination of forms can be used if symptoms do not improve.
  • The nasal spray and injectable forms work very quickly.
  • It's generally safe to use if you are pregnant.
  • Comes in a generic form, so it can be pretty cheap.
  • Relpax (eletriptan) works as well as other first choice medicines for migraines.
  • Relpax (eletriptan) comes in 2 different strengths.
Downsides and risks
ImitrexRelpax
  • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
  • Does not prevent migraine headaches; it only treats them once they start.
  • Must wait 1 hour before using second injection.
  • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
  • Need to have your blood pressure checked often, especially if you're pregnant.
  • Relpax (eletriptan) is only available as a brand name.
  • Relpax (eletriptan) can cause dizziness and might make you more likely to fall.
  • If you have more than 3 migraines a month, Relpax (eletriptan) isn't a good choice because of its side effects.
Tips from our pharmacists for people taking the medication
ImitrexRelpax
  • Take it as soon as your headache starts.
  • If you use the nasal spray, be sure to blow your nose before using it.
  • If you use the patch, put it on a dry area free of scars, tattoos, or other cuts and scrapes. Be sure to press the button to activate it.
  • If you use the injection, you can use a second injection if you still have a headache after an hour. If you have symptoms 2 hours after the injection, switch to the pill version.
  • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
  • Lie down in a dark room after taking Imitrex (Sumatriptan) to help ease the pain.
  • Relpax (eletriptan) can only treat a migraine that's already happening. Relpax (eletriptan) doesn't prevent migraines from starting.
  • Take Relpax (eletriptan) at the first sign of a migraine. You can take another dose if you don't feel better after 2 hours. Don't take more than 80 mg every 24 hours.
  • Relpax (eletriptan) can make you feel dizzy or tired when you first start taking it. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • If you find you're using the entire month's supply of Relpax (eletriptan) before your next refill, talk to your doctor to see if you should try something else.
  • Relpax (eletriptan) can cause nausea or tightness in the chest or throat. Talk to your doctor if it bothers you.
Learn more
More about ImitrexSide effectsReviews & ratingsFDA package insert
Have you used Imitrex (sumatriptan)?
Worth itNot sureNot worth it
More about RelpaxSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Relpax (eletriptan)?
Worth itNot sureNot worth it