Compare Imuran vs. Remicade

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Scroll horizontally → to see comparisons



Prevents organ rejection and relieves joint pain and inflammation. Imuran (Azathioprine) is an effective medication for the treatment of rheumatoid arthritis and transplant rejection, but comes with a heavy list of side effects.Calms down your immune system. Remicade (Infliximab) is very effective at calming down your immune system, but you have to get each dose at your doctor's office and watch out for serious side effects.
How it works
Imuran (Azathioprine) is an immunosuppressant medication. It blocks the production of the white blood cells that kill unfamiliar cells.Remicade (Infliximab) is a biologic response modifier. It works in the immune system to block a protein called TNF (tumor necrosis factor). Blocking TNF relieves symptoms and prevents disease progression.
Type of medication
Biological response modifier
Kidney transplant anti-rejection
Purine antimetabolite
Prescription only
Biological response modifier
Prescription only
Available as
  • Pill
  • Injection
Used for (click to learn more)
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Button Group. All currently active
Button Group. All currently active

Not enough reviews for this drug. Help someone out, leave a review!

Reviews for Remicade (Infliximab)
+77% vs. Imuran (Azathioprine)
+65% vs. Imuran (Azathioprine)
+62% vs. Imuran (Azathioprine)
Side effects

The Imuran FDA package insert doesn’t have numbers about how common side effects are.

More about Imuran side effects »
  • Infusion reaction 13%
  • Infections 11%
More Remicade side effects »
Risk factors for serious side effects
        • Sexually active men and women
        • Pregnant women
        • Child-bearing women
        Detailed Imuran (Azathioprine) risks & warnings »
          • History of heart failure
          • Taking other immunosuppressant drugs
          • Age 60 or older
          • Taking other immunosuppressant drugs
          • History of malignancy
          • History of neurologic condition
              Detailed Remicade (Infliximab) risks & warnings »
              Pregnancy category
              DFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              BFDA pregnancy category (Probably safe)

              Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

              See the FDA package insert
              • Drinking alcohol is okay while taking Imuran (Azathioprine).
              No specific alcohol-related info.
              No specific food-related info.No specific food-related info.
              Kidneys and liver
              No specific kidneys and liver-related info.No specific kidneys and liver-related info.
              • If you're sexually active, you and your partner should use birth control, since Imuran (Azathioprine) can cause birth defects.
              No specific sex-related info.
              No specific sleep-related info.No specific sleep-related info.
              No specific weight-related info.
              • Remicade (Infliximab) can increase your risk of serious or life-threatening bacterial, fungal and viral infections. In some cases infections can be reactivated from an inactive virus in your body like tuberculosis (TB) or hepatitis B virus (HBV). You may need to take medicine for TB before you can begin taking Remicade (Infliximab). If you develop symptoms of cough, fever, chills, muscle aches, feel very tired, or you notice dark urine, yellowing of skin/eyes, appetite/weight loss, vomiting, change in stool color, stomach discomfort, and skin rash, tell your doctor and get medical care right away.
              • Although rare, Remicade (Infliximab) can cause serious liver injury. You'll need to have your liver enzymes tested regularly. If liver enzymes are significantly elevated and you have appetite/weight loss, stomach discomfort, vomiting, and notice dark urine, yellowing of skin/eyes, change in stool color, and skin rash you should stop treatment with Remicade (Infliximab) until you can be completely assessed,
              Upsides and benefits
              • Imuran (Azathioprine) has proven to be effective in the treatment of rheumatoid arthritis.
              • Imuran (Azathioprine) decreases the pain, stiffness, and swelling that most people have with rheumatoid arthritis.
              • You can still get vaccinated for the flu while taking Imuran (Azathioprine).
              • Drinking alcohol is okay while taking Imuran (Azathioprine).
              • Most side effects are temporary.
              • Treats certain types of arthritis and gastrointestinal conditions caused by an overactive immune system.
              • Remicade has almost two decades of clinical trial data and real-life experience with millions of people who have used it.
              • Initial dosing to introduce Remicade to your body might be a hassle, but then you only need to take it every 6-8 weeks depending on your condition.
              Downsides and risks
              • If you take Imuran (Azathioprine) for rheumatoid arthritis, you'll likely need to take additional medications to control your symptoms.
              • While taking Imuran (Azathioprine), you will have to get your blood tested once a week for the first month, every other week for the second and third month, and once every month after that.
              • Along with other side effects, your hair may begin to change color or fall out when you first start taking Imuran (Azathioprine), but this is usually temporary.
              • You'll likely have to take additional medications, like methotrexate to keep your rheumatoid arthritis in remission.
              • You have to get every dose through an IV infusion at your doctor's office.
              • It's expensive because there's no generic available yet.
              • Remicade has a higher risk of serious infusion-related side effects during or after it's given since it's injected right into your veins. Your doctor can prescribe medication before your dose that may lower this risk.
              • Remicade lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
              • Not the best choice if you have heart failure.
              • Talk to your baby's doctor if you're pregnant or breast-feeding. When women in a study took Remicade (Infliximab), the medicine was found in their breast milk 2 to 3 days after each dose, and in the baby's blood 6 months after they were born.
              Tips from our pharmacists for people taking the medication
              • If you're sexually active, you and your partner should use birth control, since Imuran (Azathioprine) can cause birth defects.
              • If you take Imuran (Azathioprine) for rheumatoid arthritis, your joint damage can’t be reversed, so keep up with your physical therapy and get plenty of rest.
              • While taking Imuran (Azathioprine), your body is susceptible to infection; so be sure to wash your hands often and keep distance from with people who are sick.
              • It is typical to have some nausea when you first start taking Imuran (Azathioprine); if it's unbearable, let your doctor know.
              • Don't sun tan while taking this medication. Always use sunscreen and wear a long-sleeved shirt, pants, hat, and sunglasses.
              • Remicade (Infliximab) is a medication that's given as an infusion at your doctor's office or clinic.
              • It's very important to read the patient Medication Guide when you first start using Remicade (Infliximab).
              • It's possible to get an allergic reaction to Remicade (Infliximab) either immediately during the treatment or a several days after stopping it. Your doctor can give you medicines that'll lower this risk.
              • You'll need to have a TB test before you start taking Remicade (Infliximab) and periodically during treatment.
              • Remicade (Infliximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, cough, or flu-like symptoms. Children seem to get more infections than adults, so keep a close eye on them.
              • If you have a young child, let their doctor know if you were on Remicade (Infliximab) while pregnant or nursing. It can increase their risk of infections for several months after your last dose and can delay their vaccine schedule.
              Learn more
              More about ImuranSide effectsReviews & ratingsAlternativesFDA package insert
              More about RemicadeSide effectsReviews & ratingsAlternativesFDA package insert