Compare Invega vs. Abilify

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Invega
(paliperidone)

Abilify
(aripiprazole)

Helps control your thoughts and mood. Invega (Paliperidone) is good for treating psychosis and improving mood. It's more likely to cause hormone problems than other antipsychotics.Helps control your thoughts and mood. Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.
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Coupons for Invega
Best available price for 30 (6mg) tablets of invega
Coupons for Abilify
Best available price for 30 (5mg) tablets of abilify
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.15Invega
Reviews for Invega
29%
of people (All ages) say Invega is worth it
32%
say it works well
35%
say it's a big hassle
Have you used Invega (paliperidone)?
Worth itNot sureNot worth it
Reviews for Abilify
44%
-15% worse vs. Invega
40%
-8% worse vs. Invega
34%
-1% worse vs. Invega
252 reviews
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
Side effects
InvegaAbilify
  • Abnormally fast heart beat 5%
  • Drowsiness 2%
  • Dizziness 1%
  • Abdominal pain upper 2%
  • Dry mouth 2%
  • Heart block 1%
  • Fatigue 1%
More Invega side effects »
  • Sleepiness 20%
  • Difficulty controlling movements 17%
  • Fatigue 7%
  • Nausea 7%
  • Restlessness 8%
  • Blurred vision 8%
  • Excess drooling 6%
  • Dizziness 4%
  • Extreme restlessness 21%
  • Sleep difficulty 6%
More Abilify side effects »
How it works
InvegaAbilify
Invega (Paliperidone) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affect your thoughts and mood.Abilify (aripiprazole) is an atypical antipsychotic. It stabilizes dopamine and serotonin levels in your brain to help control your thoughts and affect mood.
Type of medication
InvegaAbilify
Prescription onlyPrescription only
Available as
InvegaAbilify
  • Extended release
  • Injection
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Used for
InvegaAbilify
Risk factors for serious side effects
InvegaAbilify
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed Invega (paliperidone) risks & warnings »
  • Elderly patients with dementia
  • Age 24 years or younger
  • Use of antidepressant medications
  • People with diabetes
  • People with high cholesterol
Detailed Abilify (aripiprazole) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
InvegaAbilify
  • Invega (Paliperidone) can increase your blood sugar and cholesterol. Invega (Paliperidone) is moderately likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
No food related info.
Sleep
InvegaAbilify
  • Can cause dizziness and drowsiness, or worsen you cholesterol and blood sugar levels.
No sleep related info.
Weight
InvegaAbilify
  • Invega (Paliperidone) can cause you to gain weight. Invega (Paliperidone) is moderately likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Sometimes causes weight gain and low blood pressure.
  • Abilify (aripiprazole) can make you gain weight, which can also increase your blood sugar and cholesterol. If you're at risk for diabetes, high blood pressure or high cholestetrol, talk to your doctor how to lower your risk.
Upsides and benefits
InvegaAbilify
  • Effective at relieving psychotic symptoms and relapse rates for people with schizophrenia.
  • Also relieves psychotic symptoms and improves mood for people with schizoaffective disorder.
  • Works just as well as other antipsychotic medicines.
  • Less likely to cause heart or liver problems than some other antipsychotic medications.
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
Downsides and risks
InvegaAbilify
  • Invega (Paliperidone) has a high risk of causing hormone problems that cause nipples to leak fluid and male breasts to grow abnormally large.
  • Sometimes causes weight gain and low blood pressure.
  • Mild risk of causing extrapyramidal symptoms (EPS): movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • Not a good choice for elderly people who have dementia.
  • All antipsychotics have side effects that make them difficult to take. You might need to try a few different medicines until you find one that works best for you.
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
Tips from our pharmacists for people taking the medication
InvegaAbilify
  • It'll take 4 to 6 weeks to see the medication's full effects on thoughts and mood.
  • Can cause dizziness and drowsiness, or worsen you cholesterol and blood sugar levels.
  • For the first week, avoid activities like driving that require you to be alert.
  • Don't worry if you see tablet shells in your stool since the medication was already absorbed by your body.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Elderly people who have dementia shouldn't take Invega (Paliperidone).
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Makes you energized. Take in the morning to avoid difficulty sleeping.
  • For the first week, avoid activities that require you to be alert.
  • May increase cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Available in pills that you take daily, and as a monthly injection.
Learn more
More about InvegaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Invega (paliperidone)?
Worth itNot sureNot worth it
More about AbilifySide effectsReviews & ratingsAlternativesFDA package insert
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it