Compare Invokamet vs. Precose

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Invokamet (canagliflozin / metformin)

Prescription only

Precose (acarbose)

Prescription only
Lowers blood sugar.

Invokamet (canagliflozin / metformin) is a combination of 2 medicines that can lower your blood sugars, but it still has to be taken twice daily.

Lowers blood sugar.

Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.

Upsides
  • Combines 2 effective anti-diabetes medicines into one pill so you don't have to take them separately.
  • Does not cause weight gain unlike other anti-diabetic medicines.
  • Not as likely to cause hypoglycemia (low blood sugar)
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
Downsides
  • Not a good option if you have worsening kidney function such as those age 65 years and up.
  • May cause increased urination.
  • More likely to cause broken bones and yeast and urinary tract infections.
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$444.76
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Lowest price near you
$30.58
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Side effects
9possible side effects
  • Yeast infection in women
    11%
  • Urinary tract infections
    6%
  • Increased urination
    5%
  • Yeast infection in men
    4%
  • Thirst
    3%
  • Vaginal itching
    2%
  • Constipation
    2%
  • Nausea
    2%
  • Abdominal pain
    2%
See more detailed side effects
3possible side effects
  • Excessive gas
    74%
  • Diarrhea
    31%
  • Stomach pain
    19%
See more detailed side effects
Risks and warnings
  • Acid buildup in the blood

    Kidney problems

    ...and 5 more risk factors

  • Low blood pressure (hypotension)

    Over age 65

    ...and 4 more risk factors

  • Bone fractures

    Low blood pressure

    ...and 1 more risk factors

  • Kidney damage

    History of kidney damage

    ...and 3 more risk factors

  • Genital yeast infection and urinary tract infection

    History of urinary tract infections

    ...and 2 more risk factors

  • Low blood sugars

    Taking other diabetic medications

    ...and 2 more risk factors

See more detailed risks and warnings
  • Low blood sugar

    Using insulin or other medicines that stimulate insulin release

  • Kidney function

    Those with kidney problems

  • Interactions with other medicines

    Taking multiple medicines together

See more detailed risks and warnings