Compare Invokana vs. Victoza

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Invokana
(canagliflozin)

Victoza
(liraglutide)

Lowers blood sugar. Invokana (canagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.Lowers your blood sugar. Victoza (liraglutide) is a medicine you inject once a day to control diabetes, but it can be expensive.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.52Invokana
Reviews for Invokana
67%
of people (All ages) say Invokana is worth it
56%
say it works well
19%
say it's a big hassle
Have you used Invokana (canagliflozin)?
Worth itNot sureNot worth it
Reviews for Victoza
73%
-6% worse vs. Invokana
91%
-35% worse vs. Invokana
27%
+8% better vs. Invokana
Have you used Victoza (liraglutide)?
Worth itNot sureNot worth it
Side effects
InvokanaVictoza
  • Yeast infection in women 8%
  • Urinary tract infections 2%
  • Increased urination 4%
  • Yeast infection in men 3%
  • Thirst 3%
  • Vaginal itching 2%
  • Constipation 1%
  • Abdominal pain 1%
More Invokana side effects »
  • Nausea 13%
  • Headache 4%
  • Diarrhea 6%
  • Low appetite 9%
  • Runny nose and congestion 1%
  • Head cold 1%
  • Vomiting 4%
  • Constipation 4%
  • Indigestion 3%
  • Back pain 1%
More Victoza side effects »
How it works
InvokanaVictoza
Invokana (canagliflozin) is an anti-diabetes medication. It lowers blood sugar by causing your body to get rid of sugar in your urine.Victoza (liraglutide) is a medication for diabetes. It stimulates your body to make and release more insulin, stops the body from releasing more sugar, and slows down digestion.
Type of medication
InvokanaVictoza
Prescription onlyPrescription only
Available as
InvokanaVictoza
  • Pill
  • Injection
Used for
InvokanaVictoza
Risk factors for serious side effects
InvokanaVictoza
  • History of amputations 
  • Peripheral vascular disease (narrowed blood vessels)
  • Nerve problems
  • Diabetic foot ulcers 
  • History of kidney damage
Detailed Invokana (canagliflozin) risks & warnings »
  • History of MTC
  • History of MEN 2
  • History of pancreatitis
  • History of gallstones
  • alcoholism
Detailed Victoza (liraglutide) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
InvokanaVictoza
  • Avoid if you are a heavy drinker of alcohol.
No alcohol related info.
Food
InvokanaVictoza
  • Take once daily before your first meal of the day.
  • You only have to take Invokana (canagliflozin) once a day before meals.
No food related info.
Kidneys and liver
InvokanaVictoza
  • Not for people with severe kidney problems.
  • Victoza (liraglutide) can cause or worsen kidney damage. This is more likely to happen if you've had nausea or vomiting, diarrhea or dehydration. Make sure to drink plenty of fluids and stay hydrated when you're sick. If you have kidney damage already, your doctor might do regular lab tests while you're taking Victoza (liraglutide) to make sure your kidneys stay healthy.
  • No limitation for people with kidney problems, but close monitoring is recommended.
Pain
InvokanaVictoza
  • Rarely, Invokana (canagliflozin) can hurt the kidneys. This is more likely to happen if you already have kidney damage, heart failure, or take certain medicines for blood pressure or anti-inflammatories (NSAIDs). Invokana (canagliflozin) can also lower your blood pressure since it makes you urinate more. Your doctor will check your kidneys by blood tests regularly, and might ask you to change how you take Invokana (canagliflozin). Make sure to stay hydrated to prevent low blood pressure and kidney problems.
No pain related info.
Weight
InvokanaVictoza
No weight related info.
  • Helps with weight loss and controls appetite.
Upsides and benefits
InvokanaVictoza
  • Lowers A1C (blood sugar) levels by 1%.
  • You only have to take Invokana (canagliflozin) once a day before meals.
  • Less likely to cause low blood sugar than other diabetes medicines.
  • Also available as a combination drug with metformin (Invokamet).
  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • Helps with weight loss and controls appetite.
  • Only medicine in this class with proven heart health benefits.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Medicine is ready to use, without need to mix.
Downsides and risks
InvokanaVictoza
  • You're more likely to have broken bones, yeast infections and urinary tract infections with Invokana (canagliflozin).
  • There's a rare but serious risk of leg and foot amputations with Invokana (canagliflozin). Talk to your doctor if you develop new pain or infections in your feet.
  • Not for people with severe kidney problems.
  • Can raise your cholesterol.
  • Avoid if you are a heavy drinker of alcohol.
  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Compared to other similar medicines, you have to inject this every day.
Tips from our pharmacists for people taking the medication
InvokanaVictoza
  • Take once daily before your first meal of the day.
  • Invokana (canagliflozin) can cause you to urinate more, so be sure to stay hydrated.
  • Can cause genital yeast infections in females and males.
  • Can cause urinary tract infections (UTI).
  • Can cause low blood sugar, so make sure to check your blood sugar if you don't feel well.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Invokana (canagliflozin).
  • Inject the dose given by your doctor daily at the same time on your belly, thighs, or the back of your upper arm. To be used with or without food.
  • You may have low appetite, nausea, vomiting, diarrhea, or stomach pain, which may get better with time.
  • Let your doctor know if you have severe and/or persistent stomach pain or nausea with or without vomiting.
  • Unused pens should be stored in the refrigerator, but the pen in use can be kept at room temperature for up to 30 days.
Learn more
More about InvokanaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Invokana (canagliflozin)?
Worth itNot sureNot worth it
More about VictozaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Victoza (liraglutide)?
Worth itNot sureNot worth it