Compare Itraconazole vs. Diflucan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sporanox
(Itraconazole)

Diflucan
(Fluconazole)

Coming soon.Kills yeast and fungus. Diflucan (Fluconazole) is a quick, cheap, and convenient way to get rid of a yeast infection. (It's used for other kinds of fungal infections, too.) You have to avoid alcohol, though.
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Reviews & ratings
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Reviews for Diflucan (Fluconazole)
75%
+75% vs. Sporanox (Itraconazole)
61%
+61% vs. Sporanox (Itraconazole)
21%
21% vs. Sporanox (Itraconazole)
Side effects
ItraconazoleDiflucan

We haven’t found good data for Itraconazole side effects.

FDA side effect reports for Itraconazole »

The Diflucan FDA package insert doesn’t have numbers about how common side effects are.

More about Diflucan side effects »
How it works
ItraconazoleDiflucan
Coming soon.Diflucan (Fluconazole) is an oral antifungal medicine. It prevents yeast and fungi from reproducing and making their protective outer cell wall.
Type of medication
ItraconazoleDiflucan
Coming soon.
AntifungalPrescription only
Available as
ItraconazoleDiflucan
  • Pill
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
ItraconazoleDiflucan
  • Aspergillosis
Risk factors for serious side effects
ItraconazoleDiflucan
Coming soon.
      Detailed Diflucan (Fluconazole) risks & warnings »
      Pregnancy category
      ItraconazoleDiflucan
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      DFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.
      • You have to avoid alcohol while on this medication.
      • Don't drink alcohol when you take this medication.
      Food
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.
      • You have to avoid having sex for at least a week after you take Fluconazole.
      • Can interact with birth control pills, so you'll need to use condoms or other barriers if you do have sex.
      • If you're taking this for a vaginal yeast infection, you only have to take it once. Don't have sex for at least 7 days.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      ItraconazoleDiflucan
      Coming soon.
      • Available in generic.
      • For women with yeast infections, you only have to take one pill one time.
      Downsides and risks
      ItraconazoleDiflucan
      Coming soon.
      • You have to avoid alcohol while on this medication.
      • You have to avoid having sex for at least a week after you take Fluconazole.
      • Can interact with birth control pills, so you'll need to use condoms or other barriers if you do have sex.
      Tips from our pharmacists for people taking the medication
      ItraconazoleDiflucan
      Coming soon.
      • If you're taking this for a vaginal yeast infection, you only have to take it once. Don't have sex for at least 7 days.
      • For other fungal infections, take it exactly how your doctor tells you to.
      • Don't drink alcohol when you take this medication.
      • If you're on birth control pills, Fluconazole can make them less effective. Consider using another method (condoms, diaphragms) along with the pills.
      • Can cause nausea, vomiting, diarrhea and headache.
      Learn more
      More about ItraconazoleSide effectsFDA package insert
      More about DiflucanSide effectsReviews & ratingsAlternativesFDA package insert