Compare Itraconazole vs. Diflucan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sporanox (itraconazole)

Prescription only

Diflucan (fluconazole)

Prescription only
Treats fungal infections.

Sporanox (itraconazole) is effective oral medication that treats many different kinds of fungal infections. However, it has the potential to interact with a lot of other medications and has a few serious but rare side effects.

Treats yeast and other fungal infections.

Diflucan (fluconazole) is a cheap and effective treatment for fungal infections.

5.3/ 7 average rating with 30 reviewsforDiflucan
Upsides
  • Sporanox (itraconazole) is effective in treating infections caused by many different types of fungi.
  • Available as a generic in the capsule form.
  • Sporanox (itraconazole) can be used by people who have kidney problems.
  • Available in a cheap generic version.
  • Single dose treatment for vaginal infections.
  • Available as a pill, liquid, or injection.
Downsides
  • The liquid solution is especially likely to cause stomach upset like nausea and diarrhea.
  • Sporanox (itraconazole) is not a good choice for simple fungal infections (like nail infections) in people who have congestive heart failure because it can cause high blood pressure and swelling of the limbs.
  • Sporanox (itraconazole) isn't absorbed in the same way by everyone. You'll likely need to get lab tests done to check on its levels in the blood.
  • Sporanox (itraconazole) can cause serious side effects like allergic reactions, liver toxicity, nerve pain, or hearing loss.
  • Sporanox (itraconazole) has a lot of drug interactions. Let your doctor or pharmacist know about all of the medications you're taking.
  • Excessive use of alcohol while on this medicine can harm your liver.
  • Can interfere with how other medicines work, especially birth control pills.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
  • Injection
Price
Lowest price near you
$147.17
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$4
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Reviews
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30 
73%
think this treatment is worth it
60%
think this treatment works well
20%
think this treatment is a hassle

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Side effects
10possible side effects
  • Nausea
    11%
  • Rash
    9%
  • Vomiting
    5%
  • Swelling due to fluid retention
    4%
  • Headache
    4%
  • Diarrhea
    3%
  • Tiredness
    3%
  • Fever
    3%
  • Itching
    3%
  • High blood pressure
    3%
See more detailed side effects
5possible side effects
  • Headache
    2%
  • Skin Rash
    2%
  • Vomiting
    2%
  • Abdominal pain
    2%
  • Diarrhea
    2%
See more detailed side effects
Risks and warnings
  • Congestive Heart Failure

    History of congestive heart failure

  • Irregular heartbeat

    Taking other medications that can produce an irregular heartbeat

See more detailed risks and warnings