Compare Januvia vs. Nesina

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Januvia
(sitagliptin)

Nesina
(Alogliptin)

Lowers your blood sugar. Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.Lowers your blood sugar. alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.34Januvia
Reviews for Januvia
44%
of people (All ages) say Januvia is worth it
34%
say it works well
17%
say it's a big hassle
143 reviews
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Nesina (Alogliptin)?
Worth itNot sureNot worth it
Side effects
JanuviaNesina
  • Diarrhea 1%
  • Common cold 2%
  • Upper respiratory infection 3%
  • Headache 1%
More Januvia side effects »

We haven’t found good data for Nesina side effects.

FDA side effect reports for Nesina »
How it works
JanuviaNesina
Januvia (sitagliptin) is an anti-diabetic drug that enhances your body's release of insulin.alogliptin is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.
Type of medication
JanuviaNesina
Prescription onlyNo lower cost generic availableNo lower cost generic available
Available as
JanuviaNesina
  • Pill
  • Pill
Used for
JanuviaNesina
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
JanuviaNesina
  • History of pancreatitis
  • High blood triglyceride levels
  • Gallstones (stones in gallbladder)
  • History of alchoholism
  • Kidney problems
Detailed Januvia (sitagliptin) risks & warnings »
    Detailed Nesina (Alogliptin) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Food
    JanuviaNesina
    • Take once a day in the morning with or without food.
    No food related info.
    Kidneys and liver
    JanuviaNesina
    • Januvia (sitagliptin) can worsen kidney problems. Your doctor may check your kidney function before and during treatment. Your doctor may have to adjust the dose or stop this medicine based on changes in kidney function.
    No kidneys and liver related info.
    Pain
    JanuviaNesina
    • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
    No pain related info.
    Weight
    JanuviaNesina
    • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
    No weight related info.
    Upsides and benefits
    JanuviaNesina
    • Oral blood sugar-lowering medicine.
    • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
    • Uses the hormones naturally produced by your body to affect how sugar is processed.
    • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
    • Oral blood sugar-lowering medicine.
    • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
    • Rarely causes low blood sugar.
    • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
    Downsides and risks
    JanuviaNesina
    • Lowers A1c (average blood sugar over time) by less than 1%.
    • Available as brand version only.
    • Some people might get frequent cold-like symptoms.
    • Rare but serious side effects include pancreatitis and severe joint pain.
    • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
    • Likely expensive since there's no generic version available.
    • Some people might get frequent throat infections or nasal congestion.
    Tips from our pharmacists for people taking the medication
    JanuviaNesina
    • Take once a day in the morning with or without food.
    • Can cause headache and cold-like symptoms.
    • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
    • Tell your doctor right away if you are experiencing severe joint pain.
    • Check your blood sugar regularly to check for low blood sugar.
    • Can cause headache and cold-like symptoms.
    • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
    • Can be expensive depending on insurance coverage.
    • Check your blood sugar regularly.
    Learn more
    More about JanuviaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Januvia (sitagliptin)?
    Worth itNot sureNot worth it
    More about NesinaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Nesina (Alogliptin)?
    Worth itNot sureNot worth it