Compare Januvia vs. Precose

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Januvia (sitagliptin)

Prescription only

Precose (acarbose)

Prescription only
Lowers your blood sugar.

Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.

3.2/ 5 average rating with 143 reviewsforJanuvia
Lowers blood sugar.

Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.

Upsides
  • Oral blood sugar-lowering medicine.
  • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
Downsides
  • Lowers A1c (average blood sugar over time) by less than 1%.
  • Available as brand version only.
  • Some people might get frequent cold-like symptoms.
  • Rare but serious side effects include pancreatitis and severe joint pain.
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
143 reviews so far
44%
saidit'sworth it
34%
saiditworked well
17%
saidit'sa big hassle

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Side effects
3possible side effects
  • Common cold
    5%
  • Diarrhea
    3%
  • Abdominal pain
    2%
See more detailed side effects
3possible side effects
  • Excessive gas
    74%
  • Diarrhea
    31%
  • Stomach pain
    19%
See more detailed side effects
Risks and risk factors
  • Death from inflammation of the pancreas (pancreatitis)
    • History of pancreatitis
    • High blood triglyceride levels
    • Gallstones (stones in gallbladder)
    • History of alchoholism
    • Kidney problems
  • Serious allergic reactions
  • Kidney damage
    • Pre-existing kidney damage
  • Low blood sugar (hypoglycemia)
    • Taking medicines for diabetes
  • Severe joint pain and swelling
See more detailed risks and warnings
  • Low blood sugar
    • Using insulin or other medicines that stimulate insulin release
  • Kidney function
    • Those with kidney problems
  • Interactions with other medicines
    • Taking multiple medicines together
See more detailed risks and warnings