Compare Januvia vs. Victoza

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Januvia
(sitagliptin)

Victoza
(liraglutide)

Lowers your blood sugar. Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.Lowers your blood sugar. Victoza (Liraglutide) helps lower blood sugar for people with diabetes and causes weight loss, but it has to be given by injection and many people have upset stomach.
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Coupons for Januvia
Best available price for 30 (100mg) tablets of sitagliptin
Coupons for Victoza
Best available price for 1 (3 pens of 18mg/3ml) carton of liraglutide
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.34Januvia
Reviews for Januvia (sitagliptin)
44%
of people (All ages) say Januvia (sitagliptin) is worth it
34%
say it works well
17%
say it's a big hassle
143 reviews
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it
Reviews for Victoza (liraglutide)
73%
+29% better vs. Januvia (sitagliptin)
91%
+57% better vs. Januvia (sitagliptin)
27%
-10% worse vs. Januvia (sitagliptin)
Have you used Victoza (liraglutide)?
Worth itNot sureNot worth it
Side effects
JanuviaVictoza
  • Common cold 2%
  • Diarrhea 1%
  • Upper respiratory infection 3%
  • Headache 1%
More Januvia side effects »
  • Nausea 26%
  • Diarrhea 17%
  • Vomiting 9%
  • Constipation 10%
More Victoza side effects »
How it works
JanuviaVictoza
Januvia (sitagliptin) is an anti-diabetic drug that enhances your body's release of insulin.Victoza (Liraglutide) is a medication for diabetes. It stimulates your body to produce and release more insulin, lower the sugar hormone (glucagon), and slow down digestion.
Type of medication
JanuviaVictoza
Prescription only
Prescription only
Available as
JanuviaVictoza
  • Pill
  • Injection
Used for
JanuviaVictoza
Risk factors for serious side effects
JanuviaVictoza
  • History of pancreatitis
  • High blood triglyceride levels
  • Gallstones (stones in gallbladder)
  • History of alchoholism
  • Kidney problems
Detailed Januvia (sitagliptin) risks & warnings »
  • Using insulin
  • Using medications that increase the amount of insulin in your body (glipizide, glyburide or glimepiride)
  • Dehydration
  • Diarrhea
  • Nausea
Detailed Victoza (liraglutide) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
JanuviaVictoza
  • Take once a day in the morning with or without food.
  • Eat regular, balanced meals to avoid low blood sugar.
Kidneys and liver
JanuviaVictoza
  • Januvia (sitagliptin) can worsen kidney problems. Your doctor may check your kidney function before and during treatment. Your doctor may have to adjust the dose or stop this medicine based on changes in kidney function.
  • There have been reports of people having kidney damage or failure while on Victoza (Liraglutide), usually when they've also had diarrhea, vomiting or nausea. Stay hydrated to prevent this from happening, or call your doctor if you're suddenly unable to urinate or the amount of urine you pass is decreased.
Pain
JanuviaVictoza
  • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
  • Using Victoza (Liraglutide) has been associated with stomach pain, nausea, vomiting and diarrhea. If you have severe gastrointestinal disease such as Crohn’s Disease or Ulcerative Colitis, you should talk to your doctor about using a different medication for diabetes.
Weight
JanuviaVictoza
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
  • Weight loss is a common side effect.
Upsides and benefits
JanuviaVictoza
  • Oral blood sugar-lowering medicine.
  • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
  • Lowers A1c levels by 1% (A1c measures your average blood sugar over time.)
  • Prevents the harmful effects of high sugar levels on your organs.
  • Taken only once a day compared to similar medications that have to be taken more often.
  • Weight loss is a common side effect.
  • Helps lower your blood sugar in combination with other medications when other medications alone aren’t working.
Downsides and risks
JanuviaVictoza
  • Lowers A1c (average blood sugar over time) by less than 1%.
  • Available as brand version only.
  • Some people might get frequent cold-like symptoms.
  • Rare but serious side effects include pancreatitis and severe joint pain.
  • Only lowers A1c levels by 1%, which may not be enough to get your blood sugar in the safe range.
  • Only available as an injectable medication; other diabetes medications can be taken by mouth.
  • Up to a third of people taking Victoza (Liraglutide) have upset stomach, and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
  • Other diabetes medications work as well and are cheaper.
  • Not considered the best first choice drug to help lower blood sugar.
Tips from our pharmacists for people taking the medication
JanuviaVictoza
  • Take once a day in the morning with or without food.
  • Can cause headache and cold-like symptoms.
  • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
  • Tell your doctor right away if you are experiencing severe joint pain.
  • Check your blood sugar regularly to check for low blood sugar.
  • Store in the refrigerator until opening.
  • Give injections in your belly, thighs, or upper arm.
  • Change the needle every time you inject.
  • It’s not safe to share this medication with other people, even if you change the needle.
  • Don’t mix with insulin; always give yourself separate injections. Can be given at the same time as insulin, but in different injection areas.
  • Eat regular, balanced meals to avoid low blood sugar.
  • It's best to check your blood sugar at least once a day using a home blood sugar monitor to make sure your medication is working and is safe. Some people may need to test more often, ask your doctor.
Learn more
More about JanuviaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it
More about VictozaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Victoza (liraglutide)?
Worth itNot sureNot worth it