Compare Jardiance vs. Invokamet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Jardiance (empagliflozin)

Prescription only
Lowers blood sugar.

Jardiance (empagliflozin) lowers blood sugar for people with diabetes, but can increase the chance of a yeast infection.

Lowers blood sugar.

Invokamet (canagliflozin / metformin) is a combination of 2 medicines that can lower your blood sugars, but it still has to be taken twice daily.

Upsides
  • Lowers A1c (average blood sugar over time) levels up to 1%.
  • Can prevent death from heart attack, stroke, or heart failure if you have pre-existing heart disease.
  • Can be easily taken orally as a pill.
  • Can cause weight loss.
  • Not likely to cause hypoglycemia or very low blood sugar.
  • Combines 2 effective anti-diabetes medicines into one pill so you don't have to take them separately.
  • Does not cause weight gain unlike other anti-diabetic medicines.
  • Not as likely to cause hypoglycemia (low blood sugar)
Downsides
  • More expensive since it's available as brand name only.
  • Can cause dehydration.
  • Not a good option if you have worsening kidney function such as those age 65 years and up.
  • May cause increased urination.
  • More likely to cause broken bones and yeast and urinary tract infections.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$448.76
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Lowest price near you
$444.76
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Reviews
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Side effects
The Jardiance (empagliflozin) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
  • Yeast infection in women
    11%
  • Urinary tract infections
    6%
  • Increased urination
    5%
  • Yeast infection in men
    4%
  • Thirst
    3%
  • Vaginal itching
    2%
  • Constipation
    2%
  • Nausea
    2%
  • Abdominal pain
    2%
See more detailed side effects
Risks and warnings
  • Low blood pressure

    Over age 65

    ...and 2 more risk factors

  • Worsening kidney function

    Dehydration

    ...and 2 more risk factors

  • Too much acid in the blood

    Type 1 diabetes

    ...and 1 more risk factors

See more detailed risks and warnings
  • Acid buildup in the blood

    Kidney problems

    ...and 5 more risk factors

  • Low blood pressure (hypotension)

    Over age 65

    ...and 4 more risk factors

  • Bone fractures

    Low blood pressure

    ...and 1 more risk factors

  • Kidney damage

    History of kidney damage

    ...and 3 more risk factors

  • Genital yeast infection and urinary tract infection

    History of urinary tract infections

    ...and 2 more risk factors

  • Low blood sugars

    Taking other diabetic medications

    ...and 2 more risk factors

See more detailed risks and warnings