Compare Kapvay vs. Adderall

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Kapvay
(Clonidine)

Adderall
(Dextroamphetamine / Amphetamine)

Treats ADHD and lowers blood pressure. Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.Helps you focus and stay alert. Adderall (Dextroamphetamine / Amphetamine) is a first-choice treatment for ADHD that's available as a generic, but it's a stimulant, so it can cause insomnia and other side effects.
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Reviews & ratings
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Reviews for Adderall (Dextroamphetamine / Amphetamine)
74%
+24% vs. Kapvay (Clonidine)
53%
+3% vs. Kapvay (Clonidine)
16%
+9% vs. Kapvay (Clonidine)
Side effects
KapvayAdderall
  • Drowsiness 34%
  • Any side effect 19%
  • Fatigue 15%
  • Irritability 5%
  • Sleep difficulty 5%
  • Headache 4%
  • Dry mouth 4%
  • Upper abdominal pain 3%
  • Emotional disorder 3%
  • Dizziness 2%
More Kapvay side effects »

The Adderall FDA package insert doesn’t have numbers about how common side effects are.

More about Adderall side effects »
How it works
KapvayAdderall
Clonidine is an alpha-2 agonist. Researchers don't know exactly how it works for ADHD. It works in the brain and lowers the activity of certain stress hormones, but it's not a stimulant like many ADHD medicines.Adderall (Dextroamphetamine / Amphetamine) is an amphetamine stimulant. Researchers don't know exactly how it works for ADHD, but it increases norepinephrine and dopamine activity in the brain, which affects attention and behavior.
Type of medication
KapvayAdderall
Antihypertensive
Alpha agonist
Prescription only
StimulantPrescription only
Available as
KapvayAdderall
  • Extended release
  • Pill
  • Extended release
Used for (click to learn more)
KapvayAdderall
Risk factors for serious side effects
KapvayAdderall
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
    Detailed Kapvay (Clonidine) risks & warnings »
    • History of heart problems
    • History of drug abuse
    • Taking more than the prescribed dose
    • History of high blood pressure
    • History of psychotic episodes
    • History of Bipolar Disorder
    • Taking with alcohol or drugs
    • Children ages 7 to 10
    Detailed Adderall (Dextroamphetamine / Amphetamine) risks & warnings »
    Pregnancy category
    KapvayAdderall
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.
    • Don't take it with alcohol or drugs.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    • Can cause trouble sleeping, so don't take it too close to bedtime.
    Weight
    No specific weight-related info.
    • Can cause blurry vision, loss of appetite, weight loss, headache, dry mouth, or anxious feelings.
    • Appetite suppression may occur. In clinical studies, long-term treatment with stimulants similar to Adderall (Dextroamphetamine / Amphetamine) caused a temporary slowing of growth rate (both height and weight) in children ages seven to ten years. Doctors should monitor children's growth during treatment.
    Upsides and benefits
    KapvayAdderall
    • Can be used alone or together with a stimulant-type medicine to treat ADHD.
    • In studies, it improved attention span and lowered hyperactivity and impulsivity in children and adolescents ages 6 to 17.
    • Also treats blood pressure and some nervous system and psychiatric conditions.
    • First-choice medication to treat ADHD.
    • Adderall (Dextroamphetamine / Amphetamine) is used in combination with counseling or other non-drug therapies to treat ADHD.
    • Available as a generic medication.
    • Available in both immediate and extended release forms.
    • The capsules can be opened, mixed in a spoonful of applesauce, and swallowed if you can't swallow the whole capsules.
    Downsides and risks
    KapvayAdderall
    • Can lower blood pressure.
    • The pill form can make some people sleepy, dizzy, and have dry mouth.
    • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Has to be taken in the morning and early afternoon, otherwise it can cause insomnia.
    • It's a controlled medication and should be locked up to prevent potential abuse.
    • Not safe for people with a history of heart problems.
    • For schooled-aged children, the second dose will likely need to be given at school.
    Tips from our pharmacists for people taking the medication
    KapvayAdderall
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    • For ADHD: Might take up to 2 weeks to see effects.
    • For high blood pressure: Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • If side effects don't go away, talk to your doctor about alternatives.
    • Don't stop taking this medicine suddenly.
    • Can cause blurry vision, loss of appetite, weight loss, headache, dry mouth, or anxious feelings.
    • Don't take it with alcohol or drugs.
    • Can cause trouble sleeping, so don't take it too close to bedtime.
    • If using the extended-release version, the first dose is best taken right after waking up in the morning.
    • Capsules can be opened and sprinkled on applesauce, which can then be swallowed without chewing.
    Learn more
    More about KapvaySide effectsReviews & ratingsAlternativesFDA package insert
    More about AdderallSide effectsReviews & ratingsAlternativesFDA package insert