Compare Kapvay vs. Dexedrine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Kapvay
(clonidine)

Dexedrine
(dextroamphetamine)

Treats attention deficit hyperactivity disorder. Kapvay (clonidine) is one of the few medicines for ADHD that isn't a stimulant and not addictive, but it can lower your blood pressure.Helps you stay awake and focus. Dexedrine (Dextroamphetamine) is an effective and cheap medication used to treat ADHD, but it can be habit-forming and is not used for long-term treatment.
Reviews & ratings
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Have you used Kapvay (clonidine)?
Worth itNot sureNot worth it
Reviews for Dexedrine
89%
-29% worse vs. Kapvay
79%
-19% worse vs. Kapvay
21%
+1% better vs. Kapvay
Have you used Dexedrine (dextroamphetamine)?
Worth itNot sureNot worth it
Side effects
KapvayDexedrine
  • Sleepiness 34%
  • Headache 4%
  • Fatigue 15%
  • Upper abdominal pain 3%
  • Irritability 5%
  • Dizziness 2%
  • Sleep difficulty 4%
  • Emotional disorder 3%
  • Nightmare 4%
  • Nausea 1%
More Kapvay side effects »

We haven’t found good data for Dexedrine side effects.

FDA side effect reports for Dexedrine »
How it works
KapvayDexedrine
Kapvay (clonidine) is an alpha-2 agonist. It's not entirely clear how it works for ADHD, but it lowers the activity of certain stress hormones in the brain.Dexedrine (Dextroamphetamine) is a stimulant. It treats narcolepsy and attention-deficit/hyperactivity disorder (ADHD) by increasing norepinephrine and dopamine activity in the brain.
Type of medication
KapvayDexedrine
Prescription onlyPrescription only
Available as
KapvayDexedrine
  • Extended release
  • Pill
  • Extended release
  • Liquid
Used for
KapvayDexedrine
Risk factors for serious side effects
KapvayDexedrine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Stopping Kapvay (clonidine) suddenly
Detailed Kapvay (clonidine) risks & warnings »
  • History of heart problems
  • History of drug abuse
  • History of psychotic episodes
  • History of bipolar disorder
  • Children
Detailed Dexedrine (dextroamphetamine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Sleep
KapvayDexedrine
  • People who take Kapvay (clonidine) can feel very sleepy during the day. It can be worse if you're taking other medicines that also make you sleepy, like pain medicines, or medicines for anxiety. Be very careful driving or doing anything that requires your full concentration until you know how your body reacts to it.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
No sleep related info.
Upsides and benefits
KapvayDexedrine
  • Can be used alone or together with a stimulant-type medicine to treat ADHD.
  • Also treats blood pressure and some nervous system and psychiatric conditions.
  • Kapvay (clonidine) is available in generic.
  • Recommended as a first-choice medication to treat ADHD in both adults and children.
  • Available as a generic, so it is cheaper than other medications used to treat ADHD.
  • Available in an immediate release and extended release form, which allows for once or twice a day dosing.
Downsides and risks
KapvayDexedrine
  • Kapvay (clonidine) is not a first choice medicine to treat ADHD.
  • Kapvay (clonidine) can make you feel very dizzy or cause low blood pressure.
  • Stopping Kapvay (clonidine) suddenly can cause your blood pressure to jump and your heart to beat very fast.
  • It can take up to two weeks of taking Kapvay (clonidine) to notice any changes in behavior.
  • Kapvay (clonidine) has to be swallowed whole, which can be hard for some children to do.
  • Fruit juice lowers the amount of Dexedrine (Dextroamphetamine) that gets into your body.
  • If you want to stop taking Dexedrine (Dextroamphetamine), you have to talk to your doctor since stopping cold turkey can cause withdrawal symptoms.
  • Dexedrine (Dextroamphetamine) is usually not used long-term since it can be habit-forming.
Tips from our pharmacists for people taking the medication
KapvayDexedrine
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • You might have to take Kapvay (clonidine) for at least two weeks before you notice any changes.
  • Don't stop taking this medicine suddenly without talking to your doctor.
  • Swallow Kapvay (clonidine) whole. Don't chew, cut or crush the pill.
  • If you forget your daily dose of Kapvay (clonidine), skip it for that day. Don't double up the next day.
  • Take your last dose before early afternoon, otherwise you won't be able to sleep.
  • Don't take with fruit juice or vitamin C, because they'll lower the amount of Dexedrine (Dextroamphetamine) that gets into your body.
  • Can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
  • If you've been taking Dexedrine (Dextroamphetamine) for a while and decide to stop it, you'll experience withdrawal symptoms if you stop it too fast.
  • Can cause reduced appetite, insomnia, and restlessness.
Learn more
More about KapvaySide effectsReviews & ratingsAlternativesFDA package insert
Have you used Kapvay (clonidine)?
Worth itNot sureNot worth it
More about DexedrineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dexedrine (dextroamphetamine)?
Worth itNot sureNot worth it