Compare Kapvay vs. Strattera

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats ADHD and lowers blood pressure. Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.Helps you focus and stay alert. Strattera (Atomoxetine) isn't considered a first-line medication for ADHD, but since it isn't a stimulant, it's still highly recommended.
How it works
Clonidine is an alpha-2 agonist. Researchers don't know exactly how it works for ADHD. It works in the brain and lowers the activity of certain stress hormones, but it's not a stimulant like many ADHD medicines.Strattera (Atomoxetine) is a norepinephrine reuptake inhibitor (non-stimulant). Researchers don't know exactly how it works for ADHD, but it increases norepinephrine activity in the brain, which affects attention and behavior.
Type of medication
Alpha agonist
Prescription only
Selective norepinephrine reuptake inhibitor (SNRI)Prescription only
Available as
  • Extended release
  • Pill
Used for (click to learn more)
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Reviews & ratings
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Reviews for Strattera (Atomoxetine)
5% vs. Kapvay (Clonidine)
18% vs. Kapvay (Clonidine)
Same vs. Kapvay (Clonidine)
Side effects
  • Drowsiness 34%
  • Any side effect 19%
  • Fatigue 15%
  • Irritability 5%
  • Sleep difficulty 5%
  • Headache 4%
  • Dry mouth 4%
  • Upper abdominal pain 3%
  • Emotional disorder 3%
  • Dizziness 2%
More Kapvay side effects »
  • Nausea 20%
  • Dry mouth 15%
  • Decreased appetite 13%
  • Abdominal pain 8%
  • Drowsiness 7%
  • Impotence 7%
  • Sleep difficulty 7%
  • Dizziness 5%
  • Constipation 5%
  • Difficulty with urination flow 5%
More Strattera side effects »
Risk factors for serious side effects
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
    Detailed Kapvay (Clonidine) risks & warnings »
    • Age below 18
      • History of heart problems
      • History of psychotic episodes
      • History of Bipolar Disorder
          • Starting Strattera (Atomoxetine) before puberty
          Detailed Strattera (Atomoxetine) risks & warnings »
          Pregnancy category
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          No specific alcohol-related info.No specific alcohol-related info.
          No specific food-related info.No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          No specific sex-related info.
          • It can cause changes in sex drive.
          • There have been reports of men having an erection lasting more than 4 hours while on Strattera (Atomoxetine). This has been rare. If not treated in time, this can cause permanent damage to your penis, including impotence. Talk to your doctor immediately or go to the emergency room if this happens.
          No specific sleep-related info.No specific sleep-related info.
          No specific weight-related info.
          • Appetite suppression may occur. In clinical studies, long-term treatment with stimulants similar to Strattera (Atomoxetine) caused a temporary slowing of growth rate (both height and weight) in children who started the medication before they started puberty. Doctors should monitor children's growth during treatment.
          Upsides and benefits
          • Can be used alone or together with a stimulant-type medicine to treat ADHD.
          • In studies, it improved attention span and lowered hyperactivity and impulsivity in children and adolescents ages 6 to 17.
          • Also treats blood pressure and some nervous system and psychiatric conditions.
          • One of the few medications used to treat ADHD that's not a stimulant.
          • It isn't a controlled substance.
          • Strattera (Atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
          • You usually only need to take it once a day.
          Downsides and risks
          • Can lower blood pressure.
          • The pill form can make some people sleepy, dizzy, and have dry mouth.
          • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          • It's a second-line medication used to treat ADHD. Other medications are usually tried first.
          • It's only available as a brand name medication, so it can be expensive.
          Tips from our pharmacists for people taking the medication
          • Can cause drowsiness, headache, dizziness, and dry mouth.
          • For ADHD: Might take up to 2 weeks to see effects.
          • For high blood pressure: Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • If side effects don't go away, talk to your doctor about alternatives.
          • Don't stop taking this medicine suddenly.
          • It can cause changes in sex drive.
          • Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
          • It can also cause changes in your mood.
          • Take it at the same time every day.
          • Common side effects include decreased appetite, nausea, and constipation.
          • The capsules can't be opened and need to be swallowed whole.
          Learn more
          More about KapvaySide effectsReviews & ratingsAlternativesFDA package insert
          More about StratteraSide effectsReviews & ratingsAlternativesFDA package insert