Compare Keflex vs. Levaquin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Keflex
(Cephalexin)

Levaquin
(Levofloxacin)

Kills bacteria. Keflex (Cephalexin) is good for treating many bacterial infections and is available as generic. However, if you are on medications to thin your blood, you can be more likely to bleed.Kills bacteria. Levaquin (Levofloxacin) is good for treating many bacterial infections and is available as generic. However, it can cause damage to your tendons, and make your skin more sensitive to the sun.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.0662739322533135Keflex
Reviews for Keflex (Cephalexin)
63%
of people say Keflex (Cephalexin) is worth it
48%
say it works well
14%
say it's a big hassle
Reviews for Levaquin (Levofloxacin)
54%
9% vs. Keflex (Cephalexin)
39%
9% vs. Keflex (Cephalexin)
29%
15% vs. Keflex (Cephalexin)
Side effects
KeflexLevaquin

The Keflex FDA package insert doesn’t have numbers about how common side effects are.

More about Keflex side effects »

The Levaquin FDA package insert doesn’t have numbers about how common side effects are.

More about Levaquin side effects »
How it works
KeflexLevaquin
Keflex (Cephalexin) is an antibiotic. It kills bacteria by preventing them from making their own protective covering.Levaquin (Levofloxacin) is an antibiotic. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
KeflexLevaquin
Antibiotic
Cephalosporin
Prescription only
Antibiotic
Fluoroquinolone
Prescription only
Available as
KeflexLevaquin
  • Pill
  • Powder for oral suspension
  • Pill
  • Liquid
Used for (click to learn more)
KeflexLevaquin
Risk factors for serious side effects
KeflexLevaquin
    Detailed Keflex (Cephalexin) risks & warnings »
    • Over 60 years of age
    • On long-term steroid use
    • Heart, kidney, or lung transplant
      • History of liver disease
      • Seizures
          • Diabetes
          • Taking medications for diabetes
              Detailed Levaquin (Levofloxacin) risks & warnings »
              Pregnancy category
              KeflexLevaquin
              BFDA pregnancy category (Probably safe)

              Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

              See the FDA package insert
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              Alcohol
              No specific alcohol-related info.No specific alcohol-related info.
              Food
              • Can be taken with or without food.
              No specific food-related info.
              Kidneys and liver
              No specific kidneys and liver-related info.No specific kidneys and liver-related info.
              Sex
              No specific sex-related info.No specific sex-related info.
              Sleep
              No specific sleep-related info.No specific sleep-related info.
              Weight
              No specific weight-related info.No specific weight-related info.
              Upsides and benefits
              KeflexLevaquin
              • Can be taken with or without food.
              • Available in generic.
              • Available in different forms: tablet, capsule, and suspension.
              • Used to treat many types of bacterial infections.
              • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
              • Available in generic.
              • Available in different forms: tablet, capsule, and suspension.
              • Used to treat many types of bacterial infections.
              • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
              Downsides and risks
              KeflexLevaquin
              • If you're on blood thinners (anticoagulants), talk to your doctor, it may make you more likely to bleed.
              • If you have to take any live vaccines, talk to your doctor. You may have to postpone it.
              • Can cause diarrhea.
              • Must be used with caution in people over 60 years of age, or who have had either an organ transplant or on long-term steroid use due to possible tendon rupture.
              • Levofloxacin can make your skin more sensitive to the sun.
              • Can't be used if you've ever had myasthenia gravis.
              • You have to space out any medications with aluminum, magnesium or zinc by at least 2 hours.
              • Can cause changes in taste, headaches, and insomnia.
              Tips from our pharmacists for people taking the medication
              KeflexLevaquin
              • Take this medication exactly as your doctor tells you to.
              • Store the suspension in the refrigerator. All other forms can be kept at room temperature.
              • Space out vitamins by a couple hours if you're taking this medication.
              • If you notice pain in your Achilles tendons, contact your doctor.
              • Wear sunscreen if you're going to be out in the sun.
              • Take the medication exactly how the doctor tells you to.
              • Take this medication with plenty of fluids.
              • Space out any medications containing aluminum, magnesium or zinc by at least 2 hours.
              • Can cause diarrhea, nausea or vomiting.
              • Can cause changes in taste, headaches and insomnia.
              Learn more
              More about KeflexSide effectsReviews & ratingsAlternativesFDA package insert
              More about LevaquinSide effectsReviews & ratingsAlternativesFDA package insert