Compare Klonopin vs. Lunesta

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Klonopin (Clonazepam)

Prescription only

Lunesta (Eszopiclone)

Prescription only
Controls seizures and helps you relax.

Klonopin (Clonazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and to treat seizures. Less severe withdrawal symptoms compared to similar drugs.

5.2/ 7 average rating with 767 reviewsforKlonopin
Helps you sleep.

Lunesta (Eszopiclone) is good for falling asleep and staying asleep. Not as habit-forming as some sleep medicines, but more likely to cause withdrawal symptoms if you stop suddenly.

4.5/ 7 average rating with 592 reviewsforLunesta
Upsides
  • Effective at relieving short-term anxiety and sleeplessness.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Can be used alone or with other medicines to treat seizures.
  • Less severe withdrawal symptoms compared to other benzodiazepines.
  • Effective at helping people fall asleep faster and sleep longer.
  • Not as habit-forming, so you can use it for longer than most other sleep medicines.
Downsides
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Most people find that it gets less effective over time.
  • More likely to cause withdrawal symptoms if you stop taking it suddenly.
  • Might not be safe if you have a history of drug or alcohol abuse, depression, lung disease, or a condition that affects metabolism.
  • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behavior so that you can sleep better naturally.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Pill
Price
Lowest price near you
$7.39
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$22.82
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Reviews
767 
70%
think this treatment is worth it
52%
think this treatment works well
14%
think this treatment is a hassle

Have you used Klonopin (Clonazepam)?

Leave a review
592 
55%
think this treatment is worth it
36%
think this treatment works well
17%
think this treatment is a hassle

Have you used Lunesta (Eszopiclone)?

Leave a review
Side effects
10possible side effects
  • Somnolence
    37%
  • Dizziness
    8%
  • Upper Respiratory Tract Infection
    8%
  • Depression
    7%
  • Fatigue
    7%
  • Coordination Abnormal
    6%
  • Ataxia
    5%
  • Memory Disturbance
    4%
  • Sinusitis
    4%
  • Influenza
    4%
See more detailed side effects
10possible side effects
  • Headache
    15%
  • Unpleasant Taste
    8%
  • Dyspepsia
    6%
  • Pain
    4%
  • Diarrhea
    4%
  • Pruritus
    4%
  • Dry Mouth
    3%
  • Abnormal Dreams
    3%
  • Neuralgia
    3%
  • Urinary Tract Infection
    3%
See more detailed side effects
Risks and warnings
  • Tolerance and dependence

    Taking more than the prescribed dose

    ...and 2 more risk factors

  • Withdrawal

    Long-term use

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Dependence and withdrawal

    Continuous use for 2 weeks or more

  • Driving impairment

    Alcohol

    ...and 2 more risk factors

  • Abnormal thoughts

    Undiagnosed psychiatric conditions

  • Sleep driving

    Taking with alcohol or drugs that acts in the brain

  • Risk of falls and injury

    Elderly

    ...and 4 more risk factors

  • Risk to fetus

    Women of childbearing age

    ...and 1 more risk factors

See more detailed risks and warnings