Compare lactulose vs. Senna

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Coming soon.Helps get things moving. Senokot (Senna) is gentle and effective, but it may be weaker than other laxatives.
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Reviews & ratings
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Reviews for Senokot (Senna)
43% vs. Generlac (Lactulose)
65% vs. Generlac (Lactulose)
10% vs. Generlac (Lactulose)
Side effects

We haven’t found good data for lactulose side effects.

FDA side effect reports for lactulose »

We haven’t found good data for Senna side effects.

FDA side effect reports for Senna »
How it works
Coming soon.Senokot (Senna) is a plant-derived stimulant laxative. It causes waves of contractions (peristalsis) in your intestine muscles to push stool through. It also makes stool more watery.
Type of medication
Coming soon.
Available as
  • Liquid
  • Pill
Used for (click to learn more)
  • Constipation Hepatic encephalopathy; Treatment and Prophylaxis
Risk factors for serious side effects
Coming soon.
  • Age 60 or greater
  • Malignancy
  • Other condition that causes blockage or narrowing of bowel
  • Age 60 or older
  • Taking medications that cause constipation
  • People who can't walk or move well (immobility)
  • Allergy or sensitivity to aloe (cross-allergic reaction)
  • Women of childbearing age
Detailed Senokot (Senna) risks & warnings »
Pregnancy category
BFDA pregnancy category (Probably safe)

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
No specific alcohol-related info.No specific alcohol-related info.
No specific food-related info.
  • Talk to you doctor about eating certain foods and getting more exercise to help prevent your constipation.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
No specific sex-related info.No specific sex-related info.
No specific sleep-related info.No specific sleep-related info.
No specific weight-related info.No specific weight-related info.
Upsides and benefits
Coming soon.
  • Senna was used over 3,500 years ago, so it's been around for a while.
  • It's clinically proven to relieve constipation from a variety of causes.
  • One of the few laxatives that can be given to children 2 and older.
  • It may not work for everyone, but people felt it was worth the hassle.
Downsides and risks
Coming soon.
  • It may be gentle, but it's not the strongest laxative for constipation.
  • Senna can cause cramping or the feeling that you "have to go right now".
Tips from our pharmacists for people taking the medication
Coming soon.
  • It's best to take it at bedtime or as your doctor has prescribed, but not for more than one week. Works in about 6-12 hours.
  • Ask your doctor about giving Senna to anyone younger than 2 years.
  • Ask your doctor before taking Senna if you have stomach pain, nausea, vomiting or had sudden changes in your stool for more than 2 weeks.
  • Check with your baby doctor before using or if you're pregnant or breastfeeding.
  • Talk to you doctor about eating certain foods and getting more exercise to help prevent your constipation.
Learn more
More about lactuloseSide effectsReviews & ratingsFDA package insert
More about SennaSide effectsReviews & ratingsAlternativesFDA package insert