Compare lactulose vs. Senna-S

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Generlac (lactulose)

Prescription only
Relieves constipation and gets rid of ammonia in people with liver problems.

Generlac (lactulose) relieves constipation and high ammonia levels, but it can take up to 48 hours to work.

Helps get things moving and softens things up.

Senna and docusate join forces to create Senna-S (Docusate / Senna), a vegetable-based laxative that gently relieves constipation.

3.3/ 5 average rating with 95 reviewsforSenna-S
Upsides
  • Generlac (lactulose) is the first-choice treatment for brain conditions caused by high ammonia levels.
  • Can be used if you have severe chronic constipation leading to blockage.
  • Available in generic.
  • Can be taken orally or rectally.
  • The combination of a laxative and stool softener might work better for people with constipation caused by medicines.
  • The laxative in Docusate/Senna was used over 3,500 years ago, so it's been around for a while.
  • Docusate/Senna is clinically proven to relieve constipation from a variety of causes.
  • One of the few laxative/stool-softener combinations that can be given to children 2 and older.
  • It may not work for everyone, but people felt it was worth the hassle.
Downsides
  • Should not be used if you are on a galactose-restricted diet.
  • Does not provide rapid relief of constipation. Talk to your doctor or pharmacist if you need quick relief.
  • Generlac (lactulose) has a very sweet flavor that most people don't like.
  • Most people felt that it's not the most effective laxative out there, but they could deal with the hassle and it worked pretty well.
  • Docusate/Senna can cause cramping or the feeling that you "have to go right now".
Used for
Dosage forms
  • Liquid
  • Powder
  • Pill
Price
No pricing information available
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Reviews
Not enough review data.Leave a review
95 reviews so far
39%
saidit'sworth it
29%
saiditworked well
22%
saidit'sa big hassle

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Side effects
The Generlac (lactulose) FDA package insert doesn’t have numbers about how common side effects are.
The Senna-S (Docusate / Senna) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Mineral imbalances
    • Taking Generlac (lactulose) for more than 6 months
    • Elderly
    • Taking medications that cause mineral imbalance
    • Not exercising regularly
  • Increased blood sugar
    • Diabetes
  • Problems during colonoscopy
See more detailed risks and warnings
  • Bowel blockage
    • Age 60 or older
    • Malignancy
    • Other condition that causes blockage or narrowing of bowel
    • Taking medications that cause constipation
  • Laxative dependence
    • Age 60 or older
    • Taking medications that cause constipation
    • People who can't walk or move well (immobility)
  • Risk to fetus
    • Women of childbearing age
  • Allergic reactions
    • Allergy or sensitivity to aloe (cross-allergic reaction)
See more detailed risks and warnings
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Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.