Compare Lamictal vs. Latuda

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Prevents seizures and stabilizes mood. Lamictal (Lamotrigine) is most useful for treating severe seizure disorders, and for bipolar disorder with more depression symptoms than manic symptoms. Just be careful to increase your dose slowly to avoid skin rash.Helps control your thoughts and mood. Latuda (Lurasidone) is good for treating schizophrenia and depression related to bipolar disorder. It's less likely to cause weight gain, cholesterol, blood sugar, and heart rhythm problems.
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Coupons for Lamictal
Best available price for 30 (100mg) tablets of lamictal
Coupons for Latuda
Best available price for 30 (40mg) tablets of latuda
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Lamictal
of people (All ages) say Lamictal is worth it
say it works well
say it's a big hassle
184 reviews
Have you used Lamictal (lamotrigine)?
Worth itNot sureNot worth it
Reviews for Latuda
+5% better vs. Lamictal
-3% worse vs. Lamictal
+7% better vs. Lamictal
Have you used Latuda (lurasidone)?
Worth itNot sureNot worth it
Side effects
  • Dizziness 25%
  • Headache 9%
  • Double vision 21%
  • Lack of muscle coordination 16%
  • Nausea 9%
  • Blurred vision 11%
  • Inflammation inside the nose 5%
  • Drowsiness 7%
  • Sore throat 1%
  • Rash 5%
More Lamictal side effects »
  • Drowsiness 12%
  • Restlessness 12%
  • Nausea 6%
  • Parkinsonism 6%
  • Any side effect 3%
  • Indigestion 2%
  • Vomiting 2%
  • Sleep difficulty 1%
  • Anxiety 3%
  • Agitation 3%
More Latuda side effects »
How it works
Lamictal (Lamotrigine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to calm nerve activity in the brain.Latuda (Lurasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar depression by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.
Type of medication
Prescription onlyPrescription only
Available as
  • Pill
  • Extended release
  • Chewable tablet
  • Dissolving tablet
  • Pill
Used for
Risk factors for serious side effects
  • History of depression
  • People also taking Depakote
  • Taking more than the prescribed dose
  • Increasing the dose too quickly
  • Taking birth control pills
Detailed Lamictal (lamotrigine) risks & warnings »
  • Elderly patients with dementia
  • Age 18 years or younger
  • Duration of treatment
  • Taking with alcohol
  • Taking other medicines that make you less alert
Detailed Latuda (lurasidone) risks & warnings »

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

No alcohol related info.
  • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
  • Take with food to avoid upset stomach.
  • Latuda (Lurasidone) can increase your blood sugar and cholesterol. However, Latuda (Lurasidone) is the least likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
Upsides and benefits
  • Effective at lowering the frequency of seizures in people with epilepsy or Lennox-Gestaut syndrome. Typically used together with other medications for severe seizure disorders.
  • Works best for partial, tonic-clonic, and absence seizures.
  • A first-line treatment for bipolar disorder. Effective long-term treatment for stabilizing mood. Prevents both depressive and manic episodes, but the effect is greater for preventing depression.
  • Doesn't require routine blood tests.
  • Has been shown in clinical studies to help people felt better and experience improvements with their thoughts and mood.
  • It’s a newer type of medication and works differently than traditional antidepressants.
  • Can be taken alone or with other medications that manage your mood.
  • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
Downsides and risks
  • Can cause double vision, dizziness, sleepiness, and headache.
  • Has the risk of a rare but life-threatening rash.
  • Can make hormonal birth control less effective.
  • Might be less effective than other medicines for treating manic episodes (acute mania) in people with bipolar disorder.
  • Certain antifungal and heart medicines can increase the amount of Latuda (Lurasidone) in your body and put you at risk for more side effects. Ask your doctor or pharmacist about any drug interactions between medicines you’re taking.
  • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
  • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
  • Elderly people who have dementia shouldn't take Latuda (Lurasidone).
Tips from our pharmacists for people taking the medication
  • Follow dose adjustments set by your doctor to minimize skin rash.
  • Take with food to avoid upset stomach.
  • Report rash, blurry vision, fever, persistent headache, or neck stiffness to your doctor.
  • Makes hormonal birth control less effective.
  • Takes 4 to 6 weeks to feel full effects on mood.
  • Take it once a day at the same time each day. It works faster when you take it with a small snack (at least 350 calories).
  • Don’t eat grapefruit or drink grapefruit juice while taking Latuda (Lurasidone). It can negatively affect how Latuda (Lurasidone) works.
  • Can cause dizziness and nausea, so avoid activities that require you to be alert until you get used to it.
  • Usually takes 4 to 6 weeks to see the full effects on your thoughts and mood, so hang in there until you find the right dose that works for you.
Learn more
More about LamictalSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lamictal (lamotrigine)?
Worth itNot sureNot worth it
More about LatudaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Latuda (lurasidone)?
Worth itNot sureNot worth it