Compare Lantus vs. Human Insulin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lantus (Insulin Glargine)

Prescription only

Humulin (Human Insulin)

Prescription only
Lowers blood sugar.

Lantus (Insulin Glargine) is a long-acting insulin that provides all-day sugar control. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.

5.1/ 7 average rating with 584 reviewsforLantus
Lowers blood sugar.

This form of insulin is one of the few medications in its class that you can get without a prescription, but it's expensive.

5.0/ 7 average rating with 57 reviewsforHuman Insulin
Upsides
  • Insulin is the most effective blood sugar-lowering medicine. When used correctly, it'll lower blood sugar every time you use it and prevent the harmful effects of high sugar levels on your organs and blood vessels.
  • Lantus is a long-lasting insulin that provides consistent, all-day sugar control with less risk of low blood sugar.
  • Dose can be easily adjusted to make a customized regimen that's tailored to your body.
  • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
  • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
  • Some types of this medication are available without a prescription.
  • Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose.
  • Available in different combinations so that you can do one shot or multiple shots a day.
Downsides
  • You have to take insulin by injection.
  • You have to check your blood sugar every day.
  • Likely to cause moderate weight gain (around 4 to 6 pounds).
  • Higher risk of low blood sugar episodes than other kinds of diabetes medicines.
  • Has to be taken exactly as directed or it can cause high or low blood sugar.
  • As with all insulins, you have to work with your doctor closely to make sure you're giving yourself the correct dose, or you can have low or high blood sugar.
Used for
Dosage forms
  • Injection
  • Injection
  • Inhaler
Price
Lowest price near you
$389.68
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Reviews
584 
67%
think this treatment is worth it
51%
think this treatment works well
14%
think this treatment is a hassle

Have you used Lantus (Insulin Glargine)?

Leave a review
57 
67%
think this treatment is worth it
46%
think this treatment works well
11%
think this treatment is a hassle

Have you used Humulin (Human Insulin)?

Leave a review
Side effects
2possible side effects
  • Angiopathy
    7%
  • Injection site pain
    3%
See more detailed side effects
The Humulin (Human Insulin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Life-threatening low blood sugar (Hypoglycemia)

    Insulin dose too high

    ...and 4 more risk factors

  • Complications due to low potassium

    Use of other medicine that lowers potassium

    ...and 1 more risk factors

See more detailed risks and warnings