Compare Lasix vs. spironolactone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lasix
(furosemide)

Aldactone
(spironolactone)

Lowers blood pressure. Removes extra water from your body. Lasix (Furosemide) is a very effective water pill and it'll certainly make you go to the bathroom more often.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Lasix
Best available price for 30 (20mg) tablets of furosemide
Coupons for spironolactone
Best available price for 30 (25mg) tablets of spironolactone
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.06Lasix
Reviews for Lasix (furosemide)
67%
of people (All ages) say Lasix (furosemide) is worth it
47%
say it works well
16%
say it's a big hassle
371 reviews
Have you used Lasix (furosemide)?
Worth itNot sureNot worth it
Reviews for Aldactone (spironolactone)
Not enough review data. Review it!
-67% worse vs. Lasix (furosemide)
Not enough review data. Review it!
-47% worse vs. Lasix (furosemide)
Not enough review data. Review it!
+16% better vs. Lasix (furosemide)
Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it
Side effects
Lasixspironolactone

The Lasix FDA package insert doesn’t have numbers about how common side effects are.

More about Lasix side effects »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »
How it works
Lasixspironolactone
Lasix (Furosemide) is a loop diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.
Type of medication
Lasixspironolactone
Prescription only
Prescription only
Available as
Lasixspironolactone
  • Pill
  • Liquid
  • Pill
Used for
Lasixspironolactone
Risk factors for serious side effects
Lasixspironolactone
  • Current electrolyte imbalance
  • History of sulfa allergies
  • Current kidney problems
  • Dose too high
  • Low blood protein
Detailed Lasix (furosemide) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed Aldactone (spironolactone) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
Lasixspironolactone
  • Requires routine blood tests to check kidney function.
  • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
Pain
Lasixspironolactone
No pain related info.
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
Upsides and benefits
Lasixspironolactone
  • A strong diuretic (water pill) that works well to get rid of extra fluids in your body through urination.
  • Lowers your blood pressure and your risk of heart attack and stroke.
  • Works better than thiazide diuretics (like Hydrochlorothiazide) at removing harmful levels of certain electrolytes, such as potassium.
  • Okay to take if you have kidney problems.
  • Has a low risk of causing muscle problems from low potassium levels in your blood.
  • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
  • Can lower blood pressure.
  • Reduces the risk of death in people with heart failure.
Downsides and risks
Lasixspironolactone
  • Makes you urinate very frequently.
  • Can cause low levels of important electrolytes, such as potassium.
  • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
  • Has many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
Tips from our pharmacists for people taking the medication
Lasixspironolactone
  • Starts working in 30 minutes.
  • Makes you urinate more often, so avoid taking it at bedtime.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
  • Don't use supplements or salt substitutes that are high in potassium.
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
  • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
  • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
Learn more
More about LasixSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lasix (furosemide)?
Worth itNot sureNot worth it
More about spironolactoneSide effectsAlternativesFDA package insert
Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it