Compare Lasix vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lasix
(furosemide)

Zestril
(lisinopril)

Lowers blood pressure. Removes extra water from your body. Lasix (Furosemide) is a very effective water pill and it'll certainly make you go to the bathroom more often.Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.06Lasix
Reviews for Lasix
67%
of people (All ages) say Lasix is worth it
47%
say it works well
16%
say it's a big hassle
371 reviews
Have you used Lasix (furosemide)?
Worth itNot sureNot worth it
Reviews for Lisinopril
61%
+6% better vs. Lasix
51%
-4% worse vs. Lasix
14%
-2% worse vs. Lasix
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
Side effects
LasixLisinopril

The Lasix FDA package insert doesn’t have numbers about how common side effects are.

More about Lasix side effects »
  • Headache 4%
  • Dizziness 4%
  • Cough 3%
  • Low blood pressure 4%
  • Chest pain 2%
  • Kidney damage 10%
  • Fainting 7%
  • High potassium 6%
More Lisinopril side effects »
How it works
LasixLisinopril
Lasix (Furosemide) is a loop diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
LasixLisinopril
Prescription onlyPrescription only
Available as
LasixLisinopril
  • Pill
  • Liquid
  • Pill
  • Liquid
Used for
LasixLisinopril
Risk factors for serious side effects
LasixLisinopril
  • Current electrolyte imbalance
  • History of sulfa allergies
  • Current kidney problems
  • Dose too high
  • Low blood protein
Detailed Lasix (furosemide) risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Use of salt substitutes
Detailed Zestril (lisinopril) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
LasixLisinopril
  • Requires routine blood tests to check kidney function.
  • You'll need to have blood tests done to check your kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Upsides and benefits
LasixLisinopril
  • A strong diuretic (water pill) that works well to get rid of extra fluids in your body through urination.
  • Lowers your blood pressure and your risk of heart attack and stroke.
  • Works better than thiazide diuretics (like Hydrochlorothiazide) at removing harmful levels of certain electrolytes, such as potassium.
  • Okay to take if you have kidney problems.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
Downsides and risks
LasixLisinopril
  • Makes you urinate very frequently.
  • Can cause low levels of important electrolytes, such as potassium.
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
Tips from our pharmacists for people taking the medication
LasixLisinopril
  • Starts working in 30 minutes.
  • Makes you urinate more often, so avoid taking it at bedtime.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Can cause dizziness the first few days you're taking it.
  • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
  • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
  • You'll need to have blood tests done to check your kidney function.
  • Don't take Zestril (lisinopril) if you're pregnant.
Learn more
More about LasixSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lasix (furosemide)?
Worth itNot sureNot worth it
More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it