Compare Latuda vs. Risperdal

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Latuda
(Lurasidone)

Risperdal
(Risperidone)

Helps control your thoughts and mood. Latuda (Lurasidone) is good for treating schizophrenia and depression related to bipolar disorder. It's less likely to cause weight gain, cholesterol, blood sugar, and heart rhythm problems.Helps control your thoughts and mood. Risperdal (Risperidone) is good for treating psychosis, mania, and irritability. Among newer antipsychotic medicines, more likely to cause side effects, especially weight gain and hormone problems.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.116279069767442Latuda
Reviews for Latuda (Lurasidone)
60%
of people say Latuda (Lurasidone) is worth it
60%
say it works well
21%
say it's a big hassle
Reviews for Risperdal (Risperidone)
48%
12% vs. Latuda (Lurasidone)
41%
19% vs. Latuda (Lurasidone)
48%
27% vs. Latuda (Lurasidone)
Side effects
LatudaRisperdal
  • Restlessness 19%
  • Drowsiness 16%
  • Parkinsonism 12%
  • Muscle twitching 6%
  • Nausea 6%
  • Any side effect 3%
  • Agitation 3%
  • Anxiety 3%
  • Indigestion 2%
  • Dizziness 2%
More Latuda side effects »
  • Relaxation or sleepiness 48%
  • Increased appetite 29%
  • Fatigue 22%
  • Parkinsonism 17%
  • Constipation 11%
  • Dizziness 11%
  • Abdominal pain upper 11%
  • Common cold 10%
  • Nausea 9%
  • Indigestion 8%
More Risperdal side effects »
How it works
LatudaRisperdal
Latuda (Lurasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar depression by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.Risperdal (Risperidone) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.
Type of medication
LatudaRisperdal
Antipsychotic
2nd generation
Prescription only
Antipsychotic
Atypical
Prescription only
Available as
LatudaRisperdal
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Used for (click to learn more)
LatudaRisperdal
Risk factors for serious side effects
LatudaRisperdal
  • Elderly patients with dementia
  • Age 18 years or younger
    • Duration of treatment
    • Taking with alcohol
    • Taking other medicines that make you less alert
      • History of diabetes
      • History of high cholesterol
      Detailed Latuda (Lurasidone) risks & warnings »
      • Elderly patients with dementia
          • History of heart problems
          • Drug interactions
            • People with diabetes
            • People with high cholesterol
            • People with diabetes
            • Alcohol
            • Taking other medicines that make you less alert
              Detailed Risperdal (Risperidone) risks & warnings »
              Pregnancy category
              LatudaRisperdal
              BFDA pregnancy category (Probably safe)

              Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

              See the FDA package insert
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              Alcohol
              • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
              No specific alcohol-related info.
              Food
              • Take it once a day at the same time each day. It works faster when you take it with a small snack (at least 350 calories).
              • Latuda (Lurasidone) can increase your blood sugar and cholesterol. However, Latuda (Lurasidone) is the least likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
              • Risperdal (Risperidone) can increase your blood sugar and cholesterol. Exercise and eat healthy food to lower your risk.
              • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
              Kidneys and liver
              No specific kidneys and liver-related info.No specific kidneys and liver-related info.
              Sex
              No specific sex-related info.No specific sex-related info.
              Sleep
              No specific sleep-related info.
              • Can cause dizziness and drowsiness.
              Weight
              • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
              • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
              • May cause weight gain and worsen cholesterol or blood sugar.
              • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
              Upsides and benefits
              LatudaRisperdal
              • Has been shown in clinical studies to help people felt better and experience improvements with their thoughts and mood.
              • It’s a newer type of medication and works differently than traditional antidepressants.
              • Can be taken alone or with other medications that manage your mood.
              • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
              • Effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior.
              • Lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
              • Antipsychotic medicines are all about equally effective.
              • Less likely to cause heart problems than some antipsychotics.
              Downsides and risks
              LatudaRisperdal
              • Certain antifungal and heart medicines can increase the amount of Latuda (Lurasidone) in your body and put you at risk for more side effects. Ask your doctor or pharmacist about any drug interactions between medicines you’re taking.
              • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
              • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
              • Elderly people who have dementia shouldn't take Latuda (Lurasidone).
              • Mild to moderate risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
              • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
              • Compared to other antipsychotics, higher risk of hormone problems that cause nipples to leak and male breasts to grow abnormally large.
              • You might need routine blood tests to check how the medicine is affecting your body.
              • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
              Tips from our pharmacists for people taking the medication
              LatudaRisperdal
              • Take it once a day at the same time each day. It works faster when you take it with a small snack (at least 350 calories).
              • Don’t eat grapefruit or drink grapefruit juice while taking Latuda (Lurasidone). It can negatively affect how Latuda (Lurasidone) works.
              • Can cause dizziness and nausea, so avoid activities that require you to be alert until you get used to it.
              • Usually takes 4 to 6 weeks to see the full effects on your thoughts and mood, so hang in there until you find the right dose that works for you.
              • Takes 4 to 6 weeks to see full effects on thoughts and mood.
              • Can cause dizziness and drowsiness.
              • For the first week, avoid activities that require you to be alert.
              • May cause weight gain and worsen cholesterol or blood sugar.
              • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
              • Elderly people with dementia shouldn't take it.
              Learn more
              More about LatudaSide effectsReviews & ratingsAlternativesFDA package insert
              More about RisperdalSide effectsReviews & ratingsAlternativesFDA package insert