Compare Latuda vs. Saphris

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Latuda
(Lurasidone)

Saphris
(Asenapine)

Helps control your thoughts and mood. Latuda (Lurasidone) is good for treating schizophrenia and depression related to bipolar disorder. It's less likely to cause weight gain, cholesterol, blood sugar, and heart rhythm problems.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.116279069767442Latuda
Reviews for Latuda (Lurasidone)
60%
of people say Latuda (Lurasidone) is worth it
60%
say it works well
21%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
LatudaSaphris
  • Restlessness 19%
  • Drowsiness 16%
  • Parkinsonism 12%
  • Muscle twitching 6%
  • Nausea 6%
  • Any side effect 3%
  • Agitation 3%
  • Anxiety 3%
  • Indigestion 2%
  • Dizziness 2%
More Latuda side effects »

We haven’t found good data for Saphris side effects.

FDA side effect reports for Saphris »
How it works
LatudaSaphris
Latuda (Lurasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar depression by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.Coming soon.
Type of medication
LatudaSaphris
Antipsychotic
2nd generation
Prescription only
Coming soon.
Available as
LatudaSaphris
  • Pill
  • Pill
Used for (click to learn more)
LatudaSaphris
  • Bipolar I disorder
Risk factors for serious side effects
LatudaSaphris
  • Elderly patients with dementia
  • Age 18 years or younger
    • Duration of treatment
    • Taking with alcohol
    • Taking other medicines that make you less alert
      • History of diabetes
      • History of high cholesterol
      Detailed Latuda (Lurasidone) risks & warnings »
      Coming soon.
      Pregnancy category
      LatudaSaphris
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
      No specific alcohol-related info.
      Food
      • Take it once a day at the same time each day. It works faster when you take it with a small snack (at least 350 calories).
      • Latuda (Lurasidone) can increase your blood sugar and cholesterol. However, Latuda (Lurasidone) is the least likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
      No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
      No specific weight-related info.
      Upsides and benefits
      LatudaSaphris
      • Has been shown in clinical studies to help people felt better and experience improvements with their thoughts and mood.
      • It’s a newer type of medication and works differently than traditional antidepressants.
      • Can be taken alone or with other medications that manage your mood.
      • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
      Coming soon.
      Downsides and risks
      LatudaSaphris
      • Certain antifungal and heart medicines can increase the amount of Latuda (Lurasidone) in your body and put you at risk for more side effects. Ask your doctor or pharmacist about any drug interactions between medicines you’re taking.
      • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
      • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
      • Elderly people who have dementia shouldn't take Latuda (Lurasidone).
      Coming soon.
      Tips from our pharmacists for people taking the medication
      LatudaSaphris
      • Take it once a day at the same time each day. It works faster when you take it with a small snack (at least 350 calories).
      • Don’t eat grapefruit or drink grapefruit juice while taking Latuda (Lurasidone). It can negatively affect how Latuda (Lurasidone) works.
      • Can cause dizziness and nausea, so avoid activities that require you to be alert until you get used to it.
      • Usually takes 4 to 6 weeks to see the full effects on your thoughts and mood, so hang in there until you find the right dose that works for you.
      Coming soon.
      Learn more
      More about LatudaSide effectsReviews & ratingsAlternativesFDA package insert
      More about SaphrisSide effectsReviews & ratingsFDA package insert