Compare Latuda vs. Saphris

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Helps control your thoughts and mood. Latuda (Lurasidone) is good for treating schizophrenia and depression related to bipolar disorder. It's less likely to cause weight gain, cholesterol, blood sugar, and heart rhythm problems.Coming soon.
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Reviews & ratings
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Reviews for Latuda (Lurasidone)
of people (All ages) say Latuda (Lurasidone) is worth it
say it works well
say it's a big hassle
Have you used Latuda (Lurasidone)?
Worth itNot sureNot worth it

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Have you used Saphris (Asenapine)?
Worth itNot sureNot worth it
Side effects
  • Drowsiness 12%
  • Restlessness 12%
  • Nausea 6%
  • Parkinsonism 6%
  • Any side effect 3%
  • Indigestion 2%
  • Vomiting 2%
  • Sleep difficulty 1%
  • Anxiety 3%
  • Agitation 3%
More Latuda side effects »

We haven’t found good data for Saphris side effects.

FDA side effect reports for Saphris »
How it works
Latuda (Lurasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar depression by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.Coming soon.
Type of medication
Prescription only
Available as
  • Pill
  • Pill
Used for
  • Bipolar I Disorder
Risk factors for serious side effects
  • Elderly patients with dementia
  • Age 18 years or younger
    • Duration of treatment
    • Taking with alcohol
    • Taking other medicines that make you less alert
      • History of diabetes
      • History of high cholesterol
      Detailed Latuda (Lurasidone) risks & warnings »
      Coming soon.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
      No alcohol related info.
      • Latuda (Lurasidone) can increase your blood sugar and cholesterol. However, Latuda (Lurasidone) is the least likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
      No food related info.
      Upsides and benefits
      • Has been shown in clinical studies to help people felt better and experience improvements with their thoughts and mood.
      • It’s a newer type of medication and works differently than traditional antidepressants.
      • Can be taken alone or with other medications that manage your mood.
      • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
      Coming soon
      Downsides and risks
      • Certain antifungal and heart medicines can increase the amount of Latuda (Lurasidone) in your body and put you at risk for more side effects. Ask your doctor or pharmacist about any drug interactions between medicines you’re taking.
      • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
      • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
      • Elderly people who have dementia shouldn't take Latuda (Lurasidone).
      Coming soon
      Tips from our pharmacists for people taking the medication
      • Take it once a day at the same time each day. It works faster when you take it with a small snack (at least 350 calories).
      • Don’t eat grapefruit or drink grapefruit juice while taking Latuda (Lurasidone). It can negatively affect how Latuda (Lurasidone) works.
      • Can cause dizziness and nausea, so avoid activities that require you to be alert until you get used to it.
      • Usually takes 4 to 6 weeks to see the full effects on your thoughts and mood, so hang in there until you find the right dose that works for you.
      Coming soon
      Learn more
      More about LatudaSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Latuda (Lurasidone)?
      Worth itNot sureNot worth it
      More about SaphrisSide effectsReviews & ratingsFDA package insert
      Have you used Saphris (Asenapine)?
      Worth itNot sureNot worth it