Compare Latuda vs. Zyprexa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Latuda (Lurasidone)

Prescription only

Zyprexa (olanzapine)

Prescription only
Helps control your thoughts and mood.

Latuda (Lurasidone) is good for treating schizophrenia and depression related to bipolar disorder. It's less likely to cause weight gain, cholesterol, blood sugar, and heart rhythm problems.

3.8/ 5 average rating with 61 reviewsforLatuda
Helps control your thoughts and mood.

Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.

3.7/ 5 average rating with 68 reviewsforZyprexa
Upsides
  • Has been shown in clinical studies to help people felt better and experience improvements with their thoughts and mood.
  • It’s a newer type of medication and works differently than traditional antidepressants.
  • Can be taken alone or with other medications that manage your mood.
  • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Less likely to cause heart problems than other antipsychotics.
  • Less likely to cause movement problems compared to older antipsychotics.
Downsides
  • Certain antifungal and heart medicines can increase the amount of Latuda (Lurasidone) in your body and put you at risk for more side effects. Ask your doctor or pharmacist about any drug interactions between medicines you’re taking.
  • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
  • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
  • Elderly people who have dementia shouldn't take Latuda (Lurasidone).
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
  • You may need routine blood tests to check how the medicine is affecting your body..
Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
  • Injection
Price
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Reviews
61 reviews so far
61%
saidit'sworth it
61%
saiditworked well
25%
saidit'sa big hassle

Have you used Latuda (Lurasidone)?

Leave a review
68 reviews so far
41%
saidit'sworth it
51%
saiditworked well
51%
saidit'sa big hassle

Have you used Zyprexa (olanzapine)?

Leave a review
Side effects
16possible side effects
  • Somnolence
    22%
  • Akathisia
    15%
  • Nausea
    12%
  • Parkinsonism
    11%
  • Any side effect
    9%
  • Vomiting
    8%
  • Dyspepsia
    8%
  • Insomnia
    8%
  • Agitation
    6%
  • Anxiety
    6%
  • Dystonia
    5%
  • Dizziness
    5%
  • Fatigue
    4%
  • Back Pain
    4%
  • Restlessness
    3%
  • Salivary hypersecretion
    2%
See more detailed side effects
9possible side effects
  • Drowsiness
    48%
  • Weight gain
    28%
  • Increased appetite
    28%
  • Headache
    17%
  • Fatigue
    14%
  • Dizziness
    7%
  • Dry Mouth
    7%
  • Abdominal pain
    6%
  • Pain in extremity
    5%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
    • Age 18 years or younger
  • Neuroleptic malignant syndrome (NMS)
  • Abnormal and involuntary muscle movements
    • Duration of treatment
  • Sedation and driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Blood disorders
  • Higher blood sugar and cholesterol
    • History of diabetes
    • History of high cholesterol
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Blood disorders
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
  • Higher blood sugar, high cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
See more detailed risks and warnings