Compare Levaquin vs. Bactrim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats bacterial infections.

Levaquin (levofloxacin) effectively treats different types of bacterial infections, but it is relatively more expensive than some of its alternatives.

3.3/ 5 average rating with 90 reviewsforLevaquin
Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

3.6/ 5 average rating with 473 reviewsforBactrim
Upsides
  • Available as a generic medicine.
  • Liquid form of Levaquin (levofloxacin) is available for those with trouble swallowing.
  • Treats a variety of bacterial infections.
  • Take only once a day.
  • Can take pill form with or without food.
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
Downsides
  • People with diabetes need to check their blood sugar levels regularly while taking Levaquin (levofloxacin).
  • Can't take Levaquin (levofloxacin) at the same time as antacids or vitamins.
  • Levaquin (levofloxacin) can increase your skin's sensitivity to sunlight and make you more likely to get a rash.
  • Relatively more expensive compared to similar alternatives.
  • Associated with serious and some potentially life-threatening side effects.
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
Price
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Reviews
90 reviews so far
53%
saidit'sworth it
40%
saiditworked well
31%
saidit'sa big hassle

Have you used Levaquin (levofloxacin)?

Leave a review
473 reviews so far
59%
saidit'sworth it
49%
saiditworked well
22%
saidit'sa big hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

Leave a review
Side effects
The Levaquin (levofloxacin) FDA package insert doesn’t have numbers about how common side effects are.
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Tendon rupture and inflammation
    • People over age 60
    • Taking steroid medicine
    • Those with kidney, heart, or lung transplants
  • Myasthenia gravis
    • Those with a history of myasthenia gravis
  • Diarrhea
  • Nerve damage
  • Changes in mood and behavior
    • Those with a history of depression
  • Effects on heartbeat
    • Those with a history of heart rhythm problems
    • Taking other medicines that also affect your heart rhythm
    • Older people
See more detailed risks and warnings
  • Diarrhea
  • Sunburn
  • Rash
  • Harm to fetus
  • Lower kidney function
    • Elderly
    • Taking other medicines that lower kidney function
See more detailed risks and warnings