Compare Levemir vs. metformin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Levemir (Insulin Detemir)

Prescription only

Glucophage (metformin)

Prescription only
Lowers blood sugar.

Levemir is a long-acting insulin that provides all-day sugar control. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.

4.4/ 7 average rating with 130 reviewsforLevemir
Lowers blood sugar.

Glucophage (metformin) is the first choice medicine to control your blood sugar and lower the risk of death from diabetes, although a few people may not tolerate the stomach side effects.

5.0/ 7 average rating with 938 reviewsformetformin
Upsides
  • Insulin is the most effective blood sugar-lowering medicine. When used correctly, it'll lower blood sugar every time you use it and prevent the harmful effects of high sugar levels on your organs and blood vessels.
  • Levemir is a long-lasting insulin that provides consistent, all-day sugar control with less risk of low blood sugar.
  • Dose can be easily adjusted to make a customized regimen that's tailored to your body.
  • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
  • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
  • Improves sugar control and lowers A1c levels as much as 2%.
  • One of the few diabetes medicines that lowers the risk of death from diabetes-related complications.
  • Doesn't cause weight gain.
  • Rarely causes low blood sugar.
Downsides
  • You have to take insulin by injection.
  • You have to check your blood sugar every day.
  • Likely to cause moderate weight gain (around 4 to 6 pounds).
  • Higher risk of low blood sugar episodes than other kinds of diabetes medicines.
  • Often causes stomach upset, like diarrhea, nausea, gas, or stomach cramping.
  • Usually not a good choice for people with kidney problems. Your doctor will tell you if Glucophage (metformin) is right for you to take.
  • Excessive or chronic alcohol use can increase the risk of a dangerous side effect.
Used for
Dosage forms
  • Injection
  • Pill
  • Extended release pill
  • Liquid
Price
Lowest price near you
$367.19
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Lowest price near you
$4
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Reviews
130 
45%
think this treatment is worth it
35%
think this treatment works well
22%
think this treatment is a hassle

Have you used Levemir (Insulin Detemir)?

Leave a review
938 
65%
think this treatment is worth it
46%
think this treatment works well
16%
think this treatment is a hassle

Have you used Glucophage (metformin)?

Leave a review
Side effects
The Levemir (Insulin Detemir) FDA package insert doesn’t have numbers about how common side effects are.
7possible side effects
  • Diarrhea
    53%
  • Nausea/vomiting
    26%
  • Gas
    12%
  • Weakness
    9%
  • Indigestion
    7%
  • Stomach pain
    6%
  • Headache
    6%
See more detailed side effects
Risks and warnings
  • Life-threatening low blood sugar (Hypoglycemia)

    Insulin dose too high

    ...and 4 more risk factors

  • Complications due to low potassium

    Use of other medicine that lowers potassium

    ...and 1 more risk factors

See more detailed risks and warnings
  • Excess lactic acid in the blood

    Kidney problems

    ...and 5 more risk factors

See more detailed risks and warnings