Compare Lexapro vs. Buspar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lexapro (escitalopram)

Prescription only

Buspar (Buspirone)

Prescription only
Improves mood and helps you relax.

Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.

4.9/ 7 average rating with 1063 reviewsforLexapro
Helps you relax.

Buspar (Buspirone) is effective for treating Generalized Anxiety Disorder (GAD), and less effective for short-term use.

4.6/ 7 average rating with 67 reviewsforBuspar
Upsides
  • Effective at relieving depression and anxiety symptoms.
  • Lowers the likelihood that your depression will come back.
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
  • Buspar (Buspirone) works very well to control the symptoms of generalized anxiety syndrome (GAD).
  • Buspar (Buspirone) doesn't cause physical dependence or withdrawal symptoms.
  • Buspar (Buspirone) is only available as a generic, so the price can be pretty cheap.
Downsides
  • Can cause a small weight gain of 1-5 pounds.
  • Lexapro (escitalopram) is not a good option if you have heart or liver problems.
  • The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
  • Buspar (Buspirone) can take as long as four weeks to become fully effective.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Most people find that it loses effectiveness over long periods of time.
  • Can cause drowsiness or dizziness when you start taking Buspar (Buspirone). Be extremely careful of activities that require mental alertness, such as driving.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
Lowest price near you
$9.9
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$4
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Reviews
1063 
61%
think this treatment is worth it
48%
think this treatment works well
15%
think this treatment is a hassle

Have you used Lexapro (escitalopram)?

Leave a review
67 
46%
think this treatment is worth it
45%
think this treatment works well
22%
think this treatment is a hassle

Have you used Buspar (Buspirone)?

Leave a review
Side effects
10possible side effects
  • Headache
    24%
  • Nausea
    18%
  • Problems ejaculating
    14%
  • Sleepiness
    13%
  • Insomnia
    12%
  • Dry mouth
    9%
  • Diarrhea
    8%
  • Fatigue
    8%
  • Decreased libido
    7%
  • Problems with orgasm
    6%
See more detailed side effects
10possible side effects
  • Dizziness
    12%
  • Any side effect
    10%
  • Drowsiness
    10%
  • Nausea
    8%
  • Headache
    6%
  • Nervousness
    5%
  • Fatigue
    4%
  • Central nervous system disturbances
    3%
  • Insomnia
    3%
  • Lightheadedness
    3%
See more detailed side effects
Risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Using other medications that affect serotonin

  • Withdrawal

    Stopping Lexapro (escitalopram) suddenly

  • Increased bleeding

    Taking blood thinners

  • Uncovering of bipolar disorder

    Bipolar disorder

See more detailed risks and warnings
  • Elevated blood pressure

    Taking with MAOIs

    ...and 1 more risk factors

  • Withdrawal reactions

    Taking with or converting from benzodiazepine medicines

  • Abnormal and involuntary muscle movements

    Duration of treatment

See more detailed risks and warnings