Compare Lexapro vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lexapro (escitalopram)

Prescription only

Oleptro (Trazodone)

Prescription only
Improves mood and helps you relax.

Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.

3.6/ 5 average rating with 1063 reviewsforLexapro
Improves mood and helps you sleep.

Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.

3.6/ 5 average rating with 59 reviewsforOleptro
Upsides
  • Effective at relieving depression and anxiety symptoms.
  • Lowers the likelihood that your depression will come back.
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Fewer sexual side effects than many other antidepressants.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
  • Can cause a small weight gain of 1-5 pounds.
  • Lexapro (escitalopram) is not a good option if you have heart or liver problems.
  • The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Extended release
Price
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Reviews
1063 reviews so far
61%
saidit'sworth it
48%
saiditworked well
15%
saidit'sa big hassle

Have you used Lexapro (escitalopram)?

Leave a review
59 reviews so far
73%
saidit'sworth it
49%
saiditworked well
24%
saidit'sa big hassle

Have you used Oleptro (Trazodone)?

Leave a review
Side effects
25possible side effects
  • Headache
    24%
  • Nausea
    18%
  • Problems ejaculating
    14%
  • Sleepiness
    13%
  • Insomnia
    12%
  • Dry mouth
    9%
  • Diarrhea
    8%
  • Fatigue
    8%
  • Decreased libido
    7%
  • Problems with orgasm
    6%
  • Constipation
    5%
  • Flu-like symptoms
    5%
  • Increased sweating
    4%
  • Indigestion
    3%
  • Vomiting
    3%
  • Neck/shoulder pain
    3%
  • Abnormal dreams
    3%
  • Decrease appetite
    3%
  • Lack of energy
    3%
  • Tingling or burning in the hands/feet
    2%
  • Abdominal pain
    2%
  • Flatulence
    2%
  • Toothache
    2%
  • Yawning
    2%
  • Menstrual disorder
    2%
See more detailed side effects
29possible side effects
  • Somnolence/Sedation
    46%
  • Drowsiness
    41%
  • Dry Mouth
    34%
  • Headache
    33%
  • Dizziness/Lightheadedness
    28%
  • Dry mouth
    25%
  • Dizziness
    25%
  • Nausea
    21%
  • Blurred Vision
    15%
  • Fatigue
    15%
  • Nausea/Vomiting
    13%
  • Diarrhea
    9%
  • Constipation
    8%
  • Skin Condition/Edema
    7%
  • Weight Loss
    6%
  • Nasal/Sinus Congestion
    6%
  • Abdominal/Gastric Disorder
    6%
  • Syncope
    5%
  • Musculoskeletal Aches/Pains
    5%
  • Tremors
    5%
  • Nightmares/Vivid Dreams
    5%
  • Weight Gain
    5%
  • Back pain
    5%
  • Vision blurred
    5%
  • Sexual dysfunction
    5%
  • Hypotension
    4%
  • Incoordination
    2%
  • Ejaculation disorders
    2%
  • Decreased libido
    2%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Withdrawal
    • Stopping Lexapro (escitalopram) suddenly
  • Increased bleeding
    • Taking blood thinners
  • Sexual problems
  • Uncovering of bipolar disorder
    • Bipolar disorder
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Seizures
    • History of seizures
    • Alcoholism
    • Eating disorder
    • Higher dose
    • Drug interactions
  • Painful erection
  • Low blood pressure
    • Age 65 years or older
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings