Compare Lexapro vs. Remeron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lexapro
(escitalopram)

Remeron
(mirtazapine)

Improves mood and helps you relax. Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.Improves mood. Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.89Lexapro
Reviews for Lexapro
61%
of people (All ages) say Lexapro is worth it
48%
say it works well
15%
say it's a big hassle
1063 reviews
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it
Reviews for Remeron
45%
+16% better vs. Lexapro
39%
+9% better vs. Lexapro
26%
+11% better vs. Lexapro
152 reviews
Have you used Remeron (mirtazapine)?
Worth itNot sureNot worth it
Side effects
LexaproRemeron
  • Nausea 8%
  • Insomnia 5%
  • Problems with ejaculation 9%
  • Diarrhea 3%
  • Dry Mouth 1%
  • Somnolence 4%
  • Runny nose 1%
  • Fatigue 3%
  • Dizziness 2%
  • Flu-like symptoms 1%
More Lexapro side effects »
  • Sleepiness 36%
  • Dry mouth 10%
  • Increased appetite   15%
  • Increased appetite 15%
  • Constipation 6%
  • Weight gain 10%
  • Lack of energy 3%
  • Dizziness 4%
  • Flu syndrome 2%
  • Abnormal dreams 3%
More Remeron side effects »
How it works
LexaproRemeron
Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin in the brain which regulates mood.Remeron (mirtazapine) is an atypical antidepressant. It stimulates your body to make certain chemicals in the brain, such as serotonin and norepinephrine, which regulate mood.
Type of medication
LexaproRemeron
Prescription onlyPrescription only
Available as
LexaproRemeron
  • Pill
  • Liquid
  • Pill
  • Dissolving tablet
Used for
LexaproRemeron
Risk factors for serious side effects
LexaproRemeron
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Lexapro (escitalopram) suddenly
  • Taking blood thinners
  • Bipolar disorder
Detailed Lexapro (escitalopram) risks & warnings »
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • History of heart problems
  • History of liver problems
  • Higher dose
Detailed Remeron (mirtazapine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
LexaproRemeron
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
  • Prescription medications can interact with Remeron (mirtazapine). Let your doctor or pharmacist know if you're on prescription medications currently or within the past 14 days.
Sleep
LexaproRemeron
No sleep related info.
  • Remeron (mirtazapine) can make you sleepy. It is best to take at bedtime.
  • Can help you fall asleep if you have trouble sleeping.
  • Makes you more tired than other antidepressants.
Weight
LexaproRemeron
  • Can cause a small weight gain of 1-5 pounds.
  • Remeron (mirtazapine) can raise your appetite and cause you to gain weight. Remeron (mirtazapine) can also raise your cholesterol.
  • Remeron (mirtazapine) can increase your appetite and cause to you to gain weight.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Upsides and benefits
LexaproRemeron
  • Effective at relieving depression and anxiety symptoms.
  • Lowers the likelihood that your depression will come back.
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
  • Effective at relieving some depression symptoms.
  • Starts to work more quickly than most antidepressants.
  • Can help you fall asleep if you have trouble sleeping.
  • Can also help relieve anxiety.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • Available as a generic.
Downsides and risks
LexaproRemeron
  • Can cause a small weight gain of 1-5 pounds.
  • Lexapro (escitalopram) is not a good option if you have heart or liver problems.
  • The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
  • Makes you more tired than other antidepressants.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Tips from our pharmacists for people taking the medication
LexaproRemeron
  • Don't suddenly stop taking DRUG NAME. Talk to your doctor about how to slowly go down in your dose to avoid withdrawal symptoms.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
  • Like other SSRI medications, it could take up to 8 weeks to see the full effects of Lexapro (escitalopram).
  • Take Lexapro (escitalopram) in the morning since it can keep you up if you take it at night.
  • Remeron (mirtazapine) can make you sleepy. It is best to take at bedtime.
  • Remeron (mirtazapine) can increase your appetite and cause to you to gain weight.
  • You should not abruptly stop Remeron (mirtazapine) as this could cause serious side effects.
  • Prescription medications can interact with Remeron (mirtazapine). Let your doctor or pharmacist know if you're on prescription medications currently or within the past 14 days.
  • Remeron (mirtazapine) should be protected from light. Keep it in it's original package until ready to use.
  • Remeron (mirtazapine) can cause dry mouth. Try using sugar-free gum or candy to help with dry mouth.
Learn more
More about LexaproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it
More about RemeronSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Remeron (mirtazapine)?
Worth itNot sureNot worth it