Compare Lexapro vs. Remeron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lexapro
(escitalopram)

Remeron
(Mirtazapine)

Improves mood and helps you relax. Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.Improves mood. Remeron (Mirtazapine) is okay for treating depression and good for sleep. More likely to cause weight gain than any other antidepressant.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.89Lexapro
Reviews for Lexapro (escitalopram)
61%
of people (All ages) say Lexapro (escitalopram) is worth it
48%
say it works well
15%
say it's a big hassle
1063 reviews
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it
Reviews for Remeron (Mirtazapine)
45%
-16% worse vs. Lexapro (escitalopram)
39%
-9% worse vs. Lexapro (escitalopram)
26%
-11% worse vs. Lexapro (escitalopram)
152 reviews
Have you used Remeron (Mirtazapine)?
Worth itNot sureNot worth it
Side effects
LexaproRemeron
  • Nausea 8%
  • Sleep difficulty 5%
  • Problems with ejaculation 9%
  • Diarrhea 3%
  • Dry mouth 1%
  • Drowsiness 4%
  • Runny nose 1%
  • Fatigue 3%
  • Dizziness 2%
  • Flu-like symptoms 1%
More Lexapro side effects »
  • Drowsiness 36%
  • Dry mouth 10%
  • Increased appetite 15%
  • Constipation 6%
  • Weight gain 10%
  • Muscle weakness 3%
  • Dizziness 4%
  • Flu syndrome 2%
  • Abnormal dreams 3%
  • Thinking abnormal 2%
More Remeron side effects »
How it works
LexaproRemeron
Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin in the brain which regulates mood.Remeron (Mirtazapine) is an atypical antidepressant. It stimulates your body to make certain chemicals in the brain, such as serotonin and norepinephrine, which regulate mood.
Type of medication
LexaproRemeron
Prescription only
Prescription only
Available as
LexaproRemeron
  • Pill
  • Liquid
  • Pill
  • Dissolving tablet
Used for
LexaproRemeron
Risk factors for serious side effects
LexaproRemeron
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Lexapro (escitalopram) suddenly
  • Taking blood thinners
    • Bipolar disorder
    Detailed Lexapro (escitalopram) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • History of heart problems
    • History of liver problems
    • Higher dose
    • Alcohol
    • Taking other medicines that make you less alert
        Detailed Remeron (Mirtazapine) risks & warnings »
        Pregnancy

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Interactions
        LexaproRemeron
        • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
        No interactions related info.
        Weight
        LexaproRemeron
        • Can cause a small weight gain of 1-5 pounds.
        • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
        • Can increase appetite and weight.
        • Remeron (Mirtazapine) can increase appetite and cause you to gain weight.
        Upsides and benefits
        LexaproRemeron
        • Effective at relieving depression and anxiety symptoms.
        • Lowers the likelihood that your depression will come back.
        • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
        • Effective at relieving some depression symptoms.
        • Starts to work more quickly than most antidepressants.
        • Might be a good option for people who have insomnia with their depression, because it can make you very sleepy.
        • Good option for people who are underweight or frail, because it can help you gain weight.
        • Six out of ten people who use an antidepressant for the first time find that it works for them.
        Downsides and risks
        LexaproRemeron
        • Can cause a small weight gain of 1-5 pounds.
        • Lexapro (escitalopram) is not a good option if you have heart or liver problems.
        • The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
        • Not as effective as other medications for depression.
        • More sedating than other antidepressants.
        • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
        • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
        • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
        Tips from our pharmacists for people taking the medication
        LexaproRemeron
        • Don't suddenly stop taking DRUG NAME. Talk to your doctor about how to slowly go down in your dose to avoid withdrawal symptoms.
        • Tell your doctor if you notice sudden mood changes or unusual thoughts.
        • Like other SSRI medications, it could take up to 8 weeks to see the full effects of Lexapro (escitalopram).
        • Take Lexapro (escitalopram) in the morning since it can keep you up if you take it at night.
        • Makes you sleepy. Take at bedtime.
        • Can increase appetite and weight.
        • Takes 8 to 12 weeks to see full effects on mood.
        • Stop taking slowly to avoid withdrawal symptoms.
        • Tell your doctor if you notice sudden mood changes or unusual thoughts.
        Learn more
        More about LexaproSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Lexapro (escitalopram)?
        Worth itNot sureNot worth it
        More about RemeronSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Remeron (Mirtazapine)?
        Worth itNot sureNot worth it