Compare Lexapro vs. nefazodone
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.
Serzone (nefazodone) is usually used with other medicines to treat depression, but it is more likely to cause liver damage.
- Effective at relieving depression and anxiety symptoms.
- Lowers the likelihood that your depression will come back.
- Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
- Serzone (nefazodone) is a good choice to take with other medicines for depression if they haven't worked by themselves.
- Serzone (nefazodone) is available in generic.
- Can cause a small weight gain of 1-5 pounds.
- Lexapro (escitalopram) is not a good option if you have heart or liver problems.
- The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
- While Serzone (nefazodone) is available as a generic, it's not considered a first or second choice medicine for depression because it is more likely to cause liver damage than other similar medicines.
- Serzone (nefazodone) is usually taken 2 times a day; the first choice medicines are only taken 1 time a day.
- It can take up to 3 months before you notice the full effects of Serzone (nefazodone).
- Compared to other similar medicines, Serzone (nefazodone) has a lot of interactions with other drugs, so your doctor might have to adjust the doses of your other medicines.
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- Problems ejaculating14%
- Dry mouth9%
- Decreased libido7%
- Problems with orgasm6%
- Dry mouth25%
- Trouble sleeping11%
- Suicidal thoughts or behavior
Age 24 years or younger
- Serotonin syndrome
Using other medications that affect serotonin
Stopping Lexapro (escitalopram) suddenly
- Increased bleeding
Taking blood thinners
- Uncovering of bipolar disorder
- Higher risk of suicide
People under age 24
- Low blood pressure
Taking medicine for high blood pressure
History of seizures
- Lower heart rate
History of heart attack or heart disease
...and 1 more risk factors