Compare Lexapro vs. Serzone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lexapro
(Escitalopram)

Serzone
(Nefazodone)

Improves mood and helps you relax. Lexapro (Escitalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.832985386221294Lexapro
Reviews for Lexapro (Escitalopram)
59%
of people say Lexapro (Escitalopram) is worth it
46%
say it works well
15%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
LexaproSerzone
  • Ejaculation disorder 12%
  • Ejaculation disorder (primarily ejaculatory delay) 11%
  • Sleep difficulty 10%
  • Nausea 10%
  • Diarrhea 9%
  • Headache 7%
  • Drowsiness 6%
  • Fatigue 6%
  • Dizziness 5%
  • Lower sex drive 5%
More Lexapro side effects »

We haven’t found good data for Serzone side effects.

FDA side effect reports for Serzone »
How it works
LexaproSerzone
Lexapro (Escitalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Coming soon.
Type of medication
LexaproSerzone
Antidepressant
Selective serotonin reuptake inhibitor (SSRI)
Prescription only
Coming soon.
Available as
LexaproSerzone
  • Pill
  • Liquid
  • Pill
Used for (click to learn more)
LexaproSerzone
  • Major depressive disorder
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.

After 4 weeks using Start and Lexapro (Escitalopram), here’s how much better people feel.

The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Serzone (Nefazodone)
Risk factors for serious side effects
LexaproSerzone
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Lexapro (Escitalopram) suddenly
  • Higher dose
  • History of heart problems
  • History of liver problems
  • Taking other blood-thinning drugs
    • History of bipolar disorder
    • At risk for bipolar disorder
    Detailed Lexapro (Escitalopram) risks & warnings »
    Coming soon.
    Pregnancy category
    LexaproSerzone
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    • Take with food to avoid upset stomach.
    No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • Lexapro (Escitalopram) can cause lower sex drive or difficulty having an orgasm. If the problem persists after the first 2 to 3 months, you can talk to your doctor about alternative antidepressants or performance-enhancing medications.
    No specific sex-related info.
    Sleep
    • Stopping Lexapro (Escitalopram) suddenly may cause withdrawal symptoms such as nausea, anxiety, agitation, flu-like symptoms, trouble sleeping, and dizziness. Withdrawal symptoms usually occur within 3 days of stopping the medication, and go away within 1 to 2 weeks. Work with your doctor to gradually reduce your dose.
    No specific sleep-related info.
    Weight
    • More likely to cause minor weight gain (1 to 5 pounds) than other antidepressants.
    No specific weight-related info.
    Upsides and benefits
    LexaproSerzone
    • Effective at relieving depression and anxiety symptoms.
    • Lowers relapse rates of depression.
    • Causes less sleepiness than some other antidepressants.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    Coming soon.
    Downsides and risks
    LexaproSerzone
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • More likely to cause minor weight gain (1 to 5 pounds) than other antidepressants.
    • Can cause an irregular heartbeat if you take a high dose (20 mg a day, or more).
    • Not a good option for you if you have heart or liver problems.
    • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
    • The first antidepressant you try doesn't always work, and might have side effects you really don't like. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    LexaproSerzone
    • Take with food to avoid upset stomach.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • Stop taking it slowly to avoid getting withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    Coming soon.
    Learn more
    More about LexaproSide effectsReviews & ratingsAlternativesFDA package insert
    More about SerzoneSide effectsFDA package insert