Compare Lexapro vs. Xanax

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lexapro
(escitalopram)

Xanax
(alprazolam)

Improves mood and helps you relax. Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.Helps you relax. Xanax (Alprazolam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and longer-term for panic attacks. More likely to cause withdrawal symptoms compared to similar drugs.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Lexapro
Best available price for 30 (10mg) tablets of lexapro
Coupons for Xanax
Best available price for 60 (0.5mg) tablets of xanax
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.89Lexapro
Reviews for Lexapro
61%
of people (All ages) say Lexapro is worth it
48%
say it works well
15%
say it's a big hassle
1063 reviews
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it
Reviews for Xanax
74%
-13% worse vs. Lexapro
55%
-7% worse vs. Lexapro
13%
-2% worse vs. Lexapro
1287 reviews
Have you used Xanax (alprazolam)?
Worth itNot sureNot worth it
Side effects
LexaproXanax
  • Nausea 8%
  • Sleep difficulty 5%
  • Problems with ejaculation 9%
  • Diarrhea 3%
  • Dry mouth 1%
  • Drowsiness 4%
  • Runny nose 1%
  • Fatigue 3%
  • Dizziness 2%
  • Flu-like symptoms 1%
More Lexapro side effects »
  • Drowsiness 34%
  • Fatigue and tiredness 6%
  • Impaired coordination 23%
  • Irritability 3%
  • Memory impairment 11%
  • Increased appetite 10%
More Xanax side effects »
How it works
LexaproXanax
Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin in the brain which regulates mood.Xanax (Alprazolam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.
Type of medication
LexaproXanax
Prescription onlyPrescription only
Available as
LexaproXanax
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Dissolving tablet
  • Liquid
Used for
LexaproXanax
Risk factors for serious side effects
LexaproXanax
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Lexapro (escitalopram) suddenly
  • Taking blood thinners
  • Bipolar disorder
Detailed Lexapro (escitalopram) risks & warnings »
  • History of drug abuse
  • Taking with alcohol or drugs
  • Taking more than 4 mg/day or longer than 12 weeks
  • Stopping Xanax (Alprazolam) suddenly
  • Severely depressed
Detailed Xanax (alprazolam) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
LexaproXanax
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
No interactions related info.
Alcohol
LexaproXanax
No alcohol related info.
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
Kidneys and liver
LexaproXanax
No kidneys and liver related info.
  • Processed by the liver, so might not be the best choice if you have liver problems.
Sleep
LexaproXanax
No sleep related info.
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
Weight
LexaproXanax
  • Can cause a small weight gain of 1-5 pounds.
No weight related info.
Upsides and benefits
LexaproXanax
  • Effective at relieving depression and anxiety symptoms.
  • Lowers the likelihood that your depression will come back.
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
  • Effective at relieving short-term anxiety.
  • Effective longer-term for panic attacks.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
Downsides and risks
LexaproXanax
  • Can cause a small weight gain of 1-5 pounds.
  • Lexapro (escitalopram) is not a good option if you have heart or liver problems.
  • The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
  • Processed by the liver, so might not be the best choice if you have liver problems.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
Tips from our pharmacists for people taking the medication
LexaproXanax
  • Don't suddenly stop taking DRUG NAME. Talk to your doctor about how to slowly go down in your dose to avoid withdrawal symptoms.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
  • Like other SSRI medications, it could take up to 8 weeks to see the full effects of Lexapro (escitalopram).
  • Take Lexapro (escitalopram) in the morning since it can keep you up if you take it at night.
  • Good for short-term relief of anxiety symptoms.
  • Starts working in 45 minutes when swallowed.
  • Can cause temporary dizziness and drowsiness.
  • Addictive. Long-term use can cause dependence or abuse.
  • Not safe to use with alcohol.
Learn more
More about LexaproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it
More about XanaxSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Xanax (alprazolam)?
Worth itNot sureNot worth it