Compare Lidocaine vs. Neurontin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lidoderm (Lidocaine)

Prescription only

Neurontin (gabapentin)

Prescription only
Treats nerve pain.

Lidoderm (Lidocaine) patches work well by releasing a local anesthetic into the skin and relieving pain by targeting damaged nerves.

5.8/ 7 average rating with 18 reviewsforLidocaine
Treats tingling and burning nerve pain.

Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.

4.6/ 7 average rating with 620 reviewsforNeurontin
Upsides
  • Lidoderm (Lidocaine) can treat pain better for people who can't take oral pain medications due to allergies or bad side effects.
  • Has been shown to relieve nerve pain due to shingles for up to 12 hours at a time.
  • Patches can be cut into smaller pieces to best fit the areas of skin they need to be used on.
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
Downsides
  • Can cause skin irritation after using it the first time, but for most people it's mild and goes away in a few minutes or hours.
  • Used patches contain enough medicine to be dangerous to children and pets, so store and dispose of the patches in a safe place out of their reach.
  • Might not be the best choice if you've had allergic reactions to numbing medications (local anesthetics) in the past.
  • Even though only small amounts of Lidoderm (Lidocaine) are absorbed into the body through the skin, if you're taking medications that treat arrhythmias, Lidoderm (Lidocaine) can affect how they work.
  • Patches shouldn't be left on for more than 12 hours, used on very large areas of skin, or covered with a heating pad.
  • Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
Used for
Dosage forms
  • Cream, gel, or ointment
  • Jelly
  • Spray
  • Topical solution
  • Patch
  • Pill
  • Oral solution
  • Extended release
Price
Lowest price near you
$8.52
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Lowest price near you
$12.05
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Reviews
18 
67%
think this treatment is worth it
72%
think this treatment works well
22%
think this treatment is a hassle

Have you used Lidoderm (Lidocaine)?

Leave a review
620 
57%
think this treatment is worth it
40%
think this treatment works well
19%
think this treatment is a hassle

Have you used Neurontin (gabapentin)?

Leave a review
Side effects
The Lidoderm (Lidocaine) FDA package insert doesn’t have numbers about how common side effects are.
The Neurontin (gabapentin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Overdose

    Use of heating pad on skin

    ...and 5 more risk factors

  • Serious allergic reaction

    Allergy to numbing medications (local anesthetics)

  • Accidental poisoning

    Not disposing of Lidoderm (Lidocaine) correctly

    ...and 1 more risk factors

  • Eye irritation

    Not washing hands after touching or applying Lidoderm (Lidocaine)

  • Skin reactions

    Applying Lidoderm (Lidocaine) to warm skin

    ...and 1 more risk factors

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

See more detailed risks and warnings
  • Neurologic and psychiatric side effects (children)

    Children ages 3 to 12

  • Driving impairment

    Taking Neurontin (gabapentin) with alcohol

    ...and 1 more risk factors

  • Withdrawal seizures

    Stopping Neurontin (gabapentin) suddenly

See more detailed risks and warnings