Compare Lidocaine vs. Norpramin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Lidoderm
(Lidocaine)

Norpramin
(Desipramine)

Treats nerve pain. Lidoderm (Lidocaine) patches work well by releasing a local anesthetic into the skin and relieving pain by targeting damaged nerves.Coming soon.
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Reviews & ratings
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Have you used Lidoderm (Lidocaine)?
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Have you used Norpramin (Desipramine)?
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Side effects
LidocaineNorpramin

The Lidocaine FDA package insert doesn’t have numbers about how common side effects are.

More about Lidocaine side effects »

We haven’t found good data for Norpramin side effects.

FDA side effect reports for Norpramin »
How it works
LidocaineNorpramin
Lidoderm (Lidocaine) is a local anesthetic. It absorbs into your skin where it targets damaged nerves and relieves burning pain.Coming soon.
Type of medication
LidocaineNorpramin
Local anestheticPrescription only
Coming soon.
Available as
LidocaineNorpramin
  • Cream, gel, or ointment
  • Jelly
  • Spray
  • Topical solution
  • Patch
  • Pill
Used for (click to learn more)
LidocaineNorpramin
  • Depression
Risk factors for serious side effects
LidocaineNorpramin
  • Use of heating pad on skin
  • Applying patch to red, irritated or broken skin
  • Leaving patch on for more than 12 hours
  • Using patch on a very large area
  • Older age and lower body weight
Detailed risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Pain
LidocaineNorpramin
  • Lidoderm (Lidocaine) can treat pain better for people who can't take oral pain medications due to allergies or bad side effects.
  • Has been shown to relieve nerve pain due to shingles for up to 12 hours at a time.
No pain related info.
Upsides and benefits
LidocaineNorpramin
  • Lidoderm (Lidocaine) can treat pain better for people who can't take oral pain medications due to allergies or bad side effects.
  • Has been shown to relieve nerve pain due to shingles for up to 12 hours at a time.
  • Patches can be cut into smaller pieces to best fit the areas of skin they need to be used on.
Coming soon
Downsides and risks
LidocaineNorpramin
  • Can cause skin irritation after using it the first time, but for most people it's mild and goes away in a few minutes or hours.
  • Used patches contain enough medicine to be dangerous to children and pets, so store and dispose of the patches in a safe place out of their reach.
  • Might not be the best choice if you've had allergic reactions to numbing medications (local anesthetics) in the past.
  • Even though only small amounts of Lidoderm (Lidocaine) are absorbed into the body through the skin, if you're taking medications that treat arrhythmias, Lidoderm (Lidocaine) can affect how they work.
  • Patches shouldn't be left on for more than 12 hours, used on very large areas of skin, or covered with a heating pad.
Coming soon
Tips from our pharmacists for people taking the medication
LidocaineNorpramin
  • Starts working with the first dose, but full effects can take longer.
  • Remove the protective lining on the patch before applying the patch to unbroken skin.
  • Leave the patch on for up to 12 hours during a 24 hour period.
  • You can cut the patches to create a custom fit for the area of skin you need to apply it to.
  • Don't place any tight wraps or heating pads over the patch while it's on.
  • Make sure not to touch your eyes after touching the patch. Always wash your hands after putting it on or taking it off.
Coming soon
Learn more
More about LidocaineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lidoderm (Lidocaine)?
Worth itNot sureNot worth it
More about NorpraminSide effectsReviews & ratingsFDA package insert
Have you used Norpramin (Desipramine)?
Worth itNot sureNot worth it