Compare Lidocaine vs. Tegretol

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Treats nerve pain. Lidoderm (Lidocaine) patches work well by releasing a local anesthetic into the skin and relieving pain by targeting damaged nerves.Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.
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Reviews & ratings
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Have you used Lidoderm (Lidocaine)?
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Reviews for Tegretol (Carbamazepine)
2% vs. Lidoderm (Lidocaine)
25% vs. Lidoderm (Lidocaine)
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Side effects

The Lidocaine FDA package insert doesn’t have numbers about how common side effects are.

More about Lidocaine side effects »
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 19%
  • Vomiting 15%
  • Itching 6%
  • Constipation 5%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Blurred vision 4%
  • Rash 3%
More Tegretol side effects »
How it works
Lidoderm (Lidocaine) is a local anesthetic. It absorbs into your skin where it targets damaged nerves and relieves burning pain.Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.
Type of medication
Local anestheticPrescription only
AnticonvulsantPrescription only
Available as
  • Cream, gel, or ointment
  • Jelly
  • Spray
  • Topical solution
  • Patch
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
Used for (click to learn more)
Risk factors for serious side effects
  • Use of heating pad on skin
  • Applying patch to red, irritated or broken skin
  • Leaving patch on for more than 12 hours
  • Using patch on a very large area
  • Older age and lower body weight
  • Liver disease
  • Allergy to numbing medications (local anesthetics)
  • Not disposing of Lidoderm (Lidocaine) correctly
  • Children and pets can reach medication
  • Not washing hands after touching or applying Lidoderm (Lidocaine)
  • Applying Lidoderm (Lidocaine) to warm skin
  • Covering patch with wrap or heating pad
  • History of heart problems
  • Using Lidoderm (Lidocaine) with drugs to treat irregular heartbeat
Detailed Lidoderm (Lidocaine) risks & warnings »
  • People also taking Depakote
  • Asian ancestry
    • History of depression
    • European, Chinese, or Japanese ancestry
      • Age 65 years or older
      • Stopping Tegretol (Carbamazepine) suddenly
      Detailed Tegretol (Carbamazepine) risks & warnings »
      Pregnancy category
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      DFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      No specific sleep related info.
      Upsides and benefits
      • Lidoderm (Lidocaine) can treat pain better for people who can't take oral pain medications due to allergies or bad side effects.
      • Has been shown to relieve nerve pain due to shingles for up to 12 hours at a time.
      • Patches can be cut into smaller pieces to best fit the areas of skin they need to be used on.
      • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
      • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
      • May be helpful in stabilizing mood for people with bipolar disorder.
      Downsides and risks
      • Can cause skin irritation after using it the first time, but for most people it's mild and goes away in a few minutes or hours.
      • Used patches contain enough medicine to be dangerous to children and pets, so store and dispose of the patches in a safe place out of their reach.
      • Might not be the best choice if you've had allergic reactions to numbing medications (local anesthetics) in the past.
      • Even though only small amounts of Lidoderm (Lidocaine) are absorbed into the body through the skin, if you're taking medications that treat arrhythmias, Lidoderm (Lidocaine) can affect how they work.
      • Patches shouldn't be left on for more than 12 hours, used on very large areas of skin, or covered with a heating pad.
      • Interacts with many other medicines and supplements.
      • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
      • Can cause blurry vision, dizziness, and upset stomach.
      • Not safe to use if you're pregnant.
      • Requires routine blood tests to see how the medicine is affecting your body.
      Tips from our pharmacists for people taking the medication
      • Starts working with the first dose, but full effects can take longer.
      • Remove the protective lining on the patch before applying the patch to unbroken skin.
      • Leave the patch on for up to 12 hours during a 24 hour period.
      • You can cut the patches to create a custom fit for the area of skin you need to apply it to.
      • Don't place any tight wraps or heating pads over the patch while it's on.
      • Make sure not to touch your eyes after touching the patch. Always wash your hands after putting it on or taking it off.
      • For the first week, avoid activities that require you to be alert.
      • Report skin rashes or blistering immediately.
      • Don't use if pregnant.
      • Requires routine blood tests.
      • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
      • Takes up to 5 weeks to feel full effects on mood.
      Learn more
      More about LidocaineSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Lidoderm (Lidocaine)?
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      More about TegretolSide effectsReviews & ratingsAlternativesFDA package insert
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