Compare Lisinopril vs. Altace

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril
(lisinopril)

Altace
(ramipril)

Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Altace (ramipril) is a good blood pressure-lowering medicine that protects your kidney function. It's also a good option if you have trouble swallowing pills since you can open the capsules.
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Coupons for Lisinopril
Best available price for 30 (20mg) tablets of lisinopril
Coupons for Altace
Best available price for 30 (10mg) capsules of ramipril
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.17Lisinopril
Reviews for Zestril (lisinopril)
61%
of people (All ages) say Zestril (lisinopril) is worth it
51%
say it works well
14%
say it's a big hassle
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
Reviews for Altace (ramipril)
Not enough review data. Review it!
-11% worse vs. Zestril (lisinopril)
Not enough review data. Review it!
-9% worse vs. Zestril (lisinopril)
Not enough review data. Review it!
-19% worse vs. Zestril (lisinopril)
Have you used Altace (ramipril)?
Worth itNot sureNot worth it
Side effects
LisinoprilAltace
  • Headache 4%
  • Dizziness 4%
  • Cough 3%
  • Low blood pressure 4%
  • Chest pain 2%
  • Kidney damage 10%
  • Fainting 7%
  • High potassium 6%
More Lisinopril side effects »
  • Low blood pressure 6%
  • Increased cough 4%
  • Dizziness 1%
  • Chest pain 1%
  • Nausea 1%
  • Low blood pressure when standing up 1%
  • Fainting 1%
  • Vomiting 1%
  • Vertigo 1%
More Altace side effects »
How it works
LisinoprilAltace
Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Altace (ramipril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that usually tightens blood vessels. By making blood vessels relax, it lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
LisinoprilAltace
Prescription only
Prescription only
Available as
LisinoprilAltace
  • Pill
  • Liquid
  • Pill
Used for
LisinoprilAltace
Risk factors for serious side effects
LisinoprilAltace
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Use of salt substitutes
Detailed Zestril (lisinopril) risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Using salt substitutes
Detailed Altace (ramipril) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
LisinoprilAltace
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • You'll need to have blood tests done to check your kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check how your kidneys are working.
Upsides and benefits
LisinoprilAltace
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
  • Altace (ramipril) is a first-choice blood pressure treatment for many people.
  • It lowers your risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Altace (ramipril) is the only ACE inhibitor that you can open and sprinkle in applesauce or water.
Downsides and risks
LisinoprilAltace
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
  • Some people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • You'll need to get routine blood tests to see how this medicine is affecting your body.
  • Women, be sure to use contraception while taking this medication since it can harm a fetus. It's also not safe to use if you're already pregnant.
Tips from our pharmacists for people taking the medication
LisinoprilAltace
  • Can cause dizziness the first few days you're taking it.
  • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
  • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
  • You'll need to have blood tests done to check your kidney function.
  • Don't take Zestril (lisinopril) if you're pregnant.
  • Altace (ramipril) can make you feel dizzy for the first few days.
  • Check your blood pressure one week after starting Altace (ramipril) or changing your dose.
  • Tell your doctor about any dizziness, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check how your kidneys are working.
  • Don't take Altace (ramipril) if you're pregnant.
  • If you can't swallow the capsule, you can open it up and mix with water, apple juice, or apple sauce.
Learn more
More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
More about AltaceSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Altace (ramipril)?
Worth itNot sureNot worth it