Compare Lisinopril vs. Atacand

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril
(lisinopril)

Atacand
(candesartan)

Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Atacand (candesartan) is a good blood pressure-lowering medicine that protects your kidneys and has few side effects.
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Prices and coupon for 30 (20mg) tablets of lisinopril
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Prices and coupon for 30 (32mg) tablets of candesartan
Reviews & ratings
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Filter group. All currently selected
5.17Lisinopril
Reviews for Zestril (lisinopril)
61%
of people (All ages) say Zestril (lisinopril) is worth it
51%
say it works well
14%
say it's a big hassle
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it

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Have you used Atacand (candesartan)?
Worth itNot sureNot worth it
Side effects
LisinoprilAtacand
  • Headache 4%
  • Dizziness 4%
  • Cough 3%
  • Low blood pressure 4%
  • Chest pain 2%
  • Kidney damage 10%
  • Fainting 7%
  • High potassium 6%
More Lisinopril side effects »
  • Upper respiratory infection 2%
  • Dizziness 1%
  • Back pain 1%
  • Sore throat 1%
  • Runny nose 1%
More Atacand side effects »
How it works
LisinoprilAtacand
Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Atacand (candesartan) is an angiotensin receptor blocker (ARB). It relaxes blood vessels by blocking a chemical that usually makes blood vessels tighter. This lowers your blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
LisinoprilAtacand
Prescription only
Prescription only
Available as
LisinoprilAtacand
  • Pill
  • Liquid
  • Pill
Used for
LisinoprilAtacand
Risk factors for serious side effects
LisinoprilAtacand
  • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
    • History of kidney problems
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    Detailed Zestril (lisinopril) risks & warnings »
    • Women of childbearing age
    • Infants less than one year old
    • History of kidney problems
    • African descent
    • Current kidney problems
    • Using medicines that increase potassium
    • Using salt substitutes
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    Detailed Atacand (candesartan) risks & warnings »
    Pregnancy

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    LisinoprilAtacand
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • You'll need to have blood tests done to check your kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • You'll need to have blood tests done regularly since Atacand (candesartan) can affect your kidneys and potassium levels.
    • Atacand (candesartan) can hurt your kidneys. If you already have some degree of kidney damage, Atacand (candesartan) could make it worse. It's important to get blood work done to check your kidney function before starting Atacand (candesartan), and at least once a year while you're still on it.
    Pain
    LisinoprilAtacand
    No pain related info.
    • Atacand (candesartan) can hurt your kidneys. If you already have some degree of kidney damage, Atacand (candesartan) could make it worse. It's important to get blood work done to check your kidney function before starting Atacand (candesartan), and at least once a year while you're still on it.
    Upsides and benefits
    LisinoprilAtacand
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Very cheap drug, and comes available as a liquid for children over 6 years of age.
    • Atacand (candesartan) lowers your risk of heart attack and stroke.
    • It works similar to ACE inhibitors (like lisinopril), but it doesn't have the same side effects like coughing and facial swelling.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • It's recommended for people with heart failure since it lowers the risk of death and further damage to your heart.
    • Can be used in children older than 12 months.
    Downsides and risks
    LisinoprilAtacand
    • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Zestril (lisinopril) isn't safe to use if you're pregnant.
    • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
    • You'll need to get yearly blood tests while taking Atacand (candesartan) to see how it is affecting your body.
    • It's not safe to use Atacand (candesartan) if you're pregnant.
    • Atacand (candesartan) can cause the level of potassium in your blood to go up.
    • You'll need to get medical help if you notice any unusual swelling around your head and neck.
    Tips from our pharmacists for people taking the medication
    LisinoprilAtacand
    • Can cause dizziness the first few days you're taking it.
    • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
    • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
    • You'll need to have blood tests done to check your kidney function.
    • Don't take Zestril (lisinopril) if you're pregnant.
    • Atacand (candesartan) can make you feel a little dizzy for the first few days.
    • You'll need to have blood tests done regularly since Atacand (candesartan) can affect your kidneys and potassium levels.
    • Don't eat a lot of foods that are high in potassium or use salt substitutes that contain potassium.
    • Tell your doctor about any dizziness or muscle weakness that doesn't go away after the first few days.
    • Don't take Atacand (candesartan) if you're pregnant.
    Learn more
    More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Zestril (lisinopril)?
    Worth itNot sureNot worth it
    More about AtacandSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Atacand (candesartan)?
    Worth itNot sureNot worth it