Compare Lisinopril vs. Avapro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril (lisinopril)

Prescription only

Avapro (irbesartan)

Prescription only
Lowers blood pressure.

Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

3.8/ 5 average rating with 687 reviewsforLisinopril
Lowers blood pressure.

Avapro (irbesartan) is a good blood pressure-lowering medicine that protects your kidneys and has few side effects.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
  • Avapro (irbesartan) lowers your risk of heart attack and stroke.
  • It works similar to ACE inhibitors (like lisinopril), but it doesn't have the same side effects like coughing and facial swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for people with heart failure since it lowers the risk of death and further damage to your heart.
  • Available in generic, and available with hydrochlorothiazide as a combination tablet.
Downsides
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
  • You'll need to get yearly blood tests while taking Avapro (irbesartan) to see how it is affecting your body.
  • It's not safe to use Avapro (irbesartan) if you're pregnant.
  • Avapro (irbesartan) can cause the level of potassium in your blood to go up.
  • You'll need to get medical help if you notice any unusual swelling around your head and neck.
  • Can't be used in children under 18.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
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Reviews
687 reviews so far
61%
saidit'sworth it
51%
saiditworked well
14%
saidit'sa big hassle

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Side effects
1possible side effects
  • Low blood pressure
    5%
See more detailed side effects
The Avapro (irbesartan) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Cough
  • Swelling of face and head
    • African descent
  • High potassium
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
  • Worsening kidney problems
    • History of kidney problems
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
See more detailed risks and warnings
  • Birth defects
    • Women of childbearing age
  • Worsening kidney problems
    • History of kidney problems
  • Swelling in the face and head
    • African descent
  • High potassium levels
    • Current kidney problems
    • Using medicines that increase potassium
    • Using salt substitutes
  • Lightheadedness & dizziness
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    • Taking diurectics (water pills)
    • Dehydration
See more detailed risks and warnings
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Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.