Compare Lisinopril vs. Captopril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril (lisinopril)

Prescription only

Capoten (Captopril)

Prescription only
Lowers blood pressure.

Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

5.2/ 7 average rating with 687 reviewsforLisinopril
Lowers blood pressure.

Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.

3.8/ 7 average rating with 106 reviewsforCaptopril
Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
Lowest price near you
$4
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Lowest price near you
$9.99
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Reviews
687 
61%
think this treatment is worth it
51%
think this treatment works well
14%
think this treatment is a hassle

Have you used Zestril (lisinopril)?

Leave a review
106 
34%
think this treatment is worth it
25%
think this treatment works well
25%
think this treatment is a hassle

Have you used Capoten (Captopril)?

Leave a review
Side effects
1possible side effects
  • Low blood pressure
    5%
See more detailed side effects
5possible side effects
  • Rash
    7%
  • Flushing
    5%
  • Dysgeusia
    4%
  • Pruritus
    2%
  • Cough
    2%
See more detailed side effects
Risks and warnings
  • Harm to fetus

    Women of childbearing age

  • Swelling of face and head

    African descent

  • High potassium

    Current kidney problems

    ...and 2 more risk factors

  • Worsening kidney problems

    History of kidney problems

  • Low blood pressure

    Taking with alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Harm to fetus

    Women of childbearing age

  • Unusual tongue swelling

    African descent

  • Heart problems due to high potassium

    Current kidney problems

    ...and 2 more risk factors

See more detailed risks and warnings