Compare Lisinopril vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril
(Lisinopril)

Coreg
(Carvedilol)

Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.164201183431953Lisinopril
Reviews for Zestril (Lisinopril)
61%
of people say Zestril (Lisinopril) is worth it
51%
say it works well
13%
say it's a big hassle
Reviews for Coreg (Carvedilol)
54%
7% vs. Zestril (Lisinopril)
46%
5% vs. Zestril (Lisinopril)
18%
5% vs. Zestril (Lisinopril)
Side effects
LisinoprilCoreg
  • Dizziness 7%
  • Headache 4%
  • Cough 3%
  • Diarrhea 2%
  • Chest pain 2%
  • Fatigue 2%
  • Upper respiratory infection 1%
More Lisinopril side effects »
  • Dizziness 13%
  • Abnormally slow heartbeat 7%
  • Low blood pressure 6%
  • Diarrhea 6%
  • High blood sugar 4%
  • Nausea 4%
  • Vision abnormal 3%
  • Fainting 3%
  • Muscle weakness 2%
  • Edema dependent 2%
More Coreg side effects »
How it works
LisinoprilCoreg
Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
LisinoprilCoreg
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
LisinoprilCoreg
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
LisinoprilCoreg
Risk factors for serious side effects
LisinoprilCoreg
  • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    Detailed Zestril (Lisinopril) risks & warnings »
    • Abrupt discontinuation of Coreg (Carvedilol)
        • Congestive heart failure
        • Increasing the dose of Coreg (Carvedilol)
        • Diabetes
        • Major surgery requiring anesthesia
          Detailed Coreg (Carvedilol) risks & warnings »
          Pregnancy category
          LisinoprilCoreg
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          No specific food-related info.
          • You have to take Carvedilol with food.
          • Take it with food.
          Kidneys and liver
          • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
          • Requires routine blood tests to check kidney function.
          No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.
          Weight
          No specific weight-related info.
          • You may notice worsening symptoms of heart failure if your prescriber decides to increase your dosage of Coreg (Carvedilol). Tell your doctor if you noticed increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as they may make changes to your medications for heart failure.
          Upsides and benefits
          LisinoprilCoreg
          • A first-choice blood pressure treatment for many people.
          • Lowers the risk of heart attack and stroke.
          • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
          • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
          • A first-choice treatment to prevent chest pain (angina).
          • A first-choice treatment for heart failure and heart attack.
          • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
          Downsides and risks
          LisinoprilCoreg
          • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
          • Requires a yearly blood test to see how the medicine is affecting your body.
          • Not safe to use if you're pregnant.
          • You have to take Carvedilol with food.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
          • Can hide symptoms of low blood sugar if you're diabetic.
          • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          Tips from our pharmacists for people taking the medication
          LisinoprilCoreg
          • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
          • Requires routine blood tests to check kidney function.
          • Don't take it if you're pregnant.
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Take it with food.
          • Can cause fatigue and erectile dysfunction.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          Learn more
          More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
          More about CoregSide effectsReviews & ratingsAlternativesFDA package insert