Compare Lisinopril vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril
(Lisinopril)

Coreg
(Carvedilol)

Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.17Lisinopril
Reviews for Zestril (Lisinopril)
61%
of people (All ages) say Zestril (Lisinopril) is worth it
51%
say it works well
14%
say it's a big hassle
687 reviews
Have you used Zestril (Lisinopril)?
Worth itNot sureNot worth it
Reviews for Coreg (Carvedilol)
53%
-8% worse vs. Zestril (Lisinopril)
46%
-5% worse vs. Zestril (Lisinopril)
18%
-4% worse vs. Zestril (Lisinopril)
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Side effects
LisinoprilCoreg
  • Headache 4%
  • Dizziness 3%
  • Cough 3%
  • Diarrhea 1%
  • Fatigue 2%
  • Infection 2%
  • Low blood pressure 4%
  • Chest pain 2%
More Lisinopril side effects »
  • Dizziness 13%
  • Fatigue 2%
  • High blood sugar 4%
  • Diarrhea 6%
  • Weight increase 3%
  • Nausea 4%
  • Abnormally slow heartbeat 8%
  • Low blood pressure 6%
  • Headache 1%
More Coreg side effects »
How it works
LisinoprilCoreg
Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
LisinoprilCoreg
Prescription only
Prescription only
Available as
LisinoprilCoreg
  • Pill
  • Pill
  • Extended release
Used for
LisinoprilCoreg
Risk factors for serious side effects
LisinoprilCoreg
  • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    Detailed Zestril (Lisinopril) risks & warnings »
    • Abrupt discontinuation of Coreg (Carvedilol)
        • Congestive heart failure
        • Increasing the dose of Coreg (Carvedilol)
        • Diabetes
        • Major surgery requiring anesthesia
          Detailed Coreg (Carvedilol) risks & warnings »
          Pregnancy

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          Food
          LisinoprilCoreg
          No food related info.
          • You have to take Carvedilol with food.
          • Take it with food.
          Kidneys and liver
          LisinoprilCoreg
          • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
          • Requires routine blood tests to check kidney function.
          No kidneys and liver related info.
          Upsides and benefits
          LisinoprilCoreg
          • A first-choice blood pressure treatment for many people.
          • Lowers the risk of heart attack and stroke.
          • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
          • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
          • A first-choice treatment to prevent chest pain (angina).
          • A first-choice treatment for heart failure and heart attack.
          • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
          Downsides and risks
          LisinoprilCoreg
          • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
          • Requires a yearly blood test to see how the medicine is affecting your body.
          • Not safe to use if you're pregnant.
          • You have to take Carvedilol with food.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
          • Can hide symptoms of low blood sugar if you're diabetic.
          • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          Tips from our pharmacists for people taking the medication
          LisinoprilCoreg
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
          • Requires routine blood tests to check kidney function.
          • Don't take it if you're pregnant.
          • Take it with food.
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Can cause fatigue and erectile dysfunction.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          Learn more
          More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
          Have you used Zestril (Lisinopril)?
          Worth itNot sureNot worth it
          More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
          Have you used Coreg (Carvedilol)?
          Worth itNot sureNot worth it