Compare Lisinopril vs. Diovan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril
(Lisinopril)

Diovan
(Valsartan)

Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Diovan (Valsartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.17Lisinopril
Reviews for Zestril (Lisinopril)
61%
of people (All ages) say Zestril (Lisinopril) is worth it
51%
say it works well
14%
say it's a big hassle
687 reviews
Have you used Zestril (Lisinopril)?
Worth itNot sureNot worth it
Reviews for Diovan (Valsartan)
65%
+4% vs. Zestril (Lisinopril)
54%
+3% vs. Zestril (Lisinopril)
15%
1% vs. Zestril (Lisinopril)
431 reviews
Have you used Diovan (Valsartan)?
Worth itNot sureNot worth it
Side effects
LisinoprilDiovan

The Lisinopril FDA package insert doesn’t have numbers about how common side effects are.

More about Lisinopril side effects »

The Diovan FDA package insert doesn’t have numbers about how common side effects are.

More about Diovan side effects »
How it works
LisinoprilDiovan
Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Diovan (Valsartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
LisinoprilDiovan
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
Angiotensin receptor blocker
Prescription only
Available as
LisinoprilDiovan
  • Pill
  • Pill
Used for (click to learn more)
LisinoprilDiovan
Risk factors for serious side effects
LisinoprilDiovan
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
LisinoprilDiovan
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
Upsides and benefits
LisinoprilDiovan
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides and risks
LisinoprilDiovan
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
LisinoprilDiovan
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
Learn more
More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zestril (Lisinopril)?
Worth itNot sureNot worth it
More about DiovanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Diovan (Valsartan)?
Worth itNot sureNot worth it