Compare Lithium vs. Latuda

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lithobid (Lithium)

Prescription only

Latuda (Lurasidone)

Prescription only
Stabilizes mood.

Lithobid (Lithium) is the most effective long-term treatment for bipolar disorder, but it comes with a lot of side effects, so it can be difficult to take.

Helps control your thoughts and mood.

Latuda (Lurasidone) is good for treating schizophrenia and depression related to bipolar disorder. It's less likely to cause weight gain, cholesterol, blood sugar, and heart rhythm problems.

5.2/ 7 average rating with 61 reviewsforLatuda
Upsides
  • A first-line, long-term treatment for bipolar disorder. Effective at stabilizing mood and preventing relapse.
  • For manic episodes (acute mania), more effective when taken together with an antipsychotic medicine.
  • The only drug proven (so far) to lower the risk of suicide, possibly because it lowers aggressiveness and impulsivity.
  • Has been shown in clinical studies to help people felt better and experience improvements with their thoughts and mood.
  • It’s a newer type of medication and works differently than traditional antidepressants.
  • Can be taken alone or with other medications that manage your mood.
  • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
Downsides
  • Has many short- and long-term side effects.
  • The dose for it to work well is very close to the amount that causes overdose, so you have to be careful, watch out for symptoms, and get help immediately if you accidentally take too much.
  • Probably not safe if you have kidney problems.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.
  • Certain antifungal and heart medicines can increase the amount of Latuda (Lurasidone) in your body and put you at risk for more side effects. Ask your doctor or pharmacist about any drug interactions between medicines you’re taking.
  • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
  • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
  • Elderly people who have dementia shouldn't take Latuda (Lurasidone).
Used for
Dosage forms
  • Pill
  • Extended release
  • Oral solution
  • Pill
Price
Lowest price near you
$4
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Lowest price near you
$1055
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Reviews
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61 
61%
think this treatment is worth it
61%
think this treatment works well
25%
think this treatment is a hassle

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Side effects
The Lithobid (Lithium) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
  • Somnolence
    22%
  • Akathisia
    15%
  • Nausea
    12%
  • Parkinsonism
    11%
  • Any side effect
    9%
  • Vomiting
    8%
  • Dyspepsia
    8%
  • Insomnia
    8%
  • Agitation
    6%
  • Anxiety
    6%
See more detailed side effects
Risks and warnings
  • Overdose

    Low sodium

    ...and 2 more risk factors

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

  • Reduced kidney function

    Long-term use

See more detailed risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Suicidal thoughts or behavior

    Age 18 years or younger

  • Abnormal and involuntary muscle movements

    Duration of treatment

  • Sedation and driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Higher blood sugar and cholesterol

    History of diabetes

    ...and 1 more risk factors

See more detailed risks and warnings