Compare Lodine vs. Morphine Sulfate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lodine
(etodolac)

Ms Contin
(morphine sulfate)

Coming soon.Treats severe pain. Ms Contin (Morphine Sulfate) provides good long-term pain control without the need to take medicine frequently, but watch out for constipation.
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Coupons for Lodine
Best available price for 60 (300mg) capsules of etodolac
Coupons for Morphine Sulfate
Best available price for 120 (15mg) tablets of morphine
Reviews & ratings
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Have you used Lodine (etodolac)?
Worth itNot sureNot worth it
Reviews for Morphine Sulfate
55%
-25% worse vs. Lodine
43%
-23% worse vs. Lodine
20%
+10% better vs. Lodine
541 reviews
Have you used Ms Contin (morphine sulfate)?
Worth itNot sureNot worth it
Side effects
LodineMorphine Sulfate

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »

The Morphine Sulfate FDA package insert doesn’t have numbers about how common side effects are.

More about Morphine Sulfate side effects »
How it works
LodineMorphine Sulfate
Coming soon.Ms Contin (Morphine Sulfate) is an opioid medicine that works in the brain to lower pain perception.
Type of medication
LodineMorphine Sulfate
Prescription only
Available as
LodineMorphine Sulfate
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Oral solution
  • Liquid
  • Suppository
Used for
LodineMorphine Sulfate
  • Juvenile Rheumatoid Arthritis Osteoarthritis Pain Rheumatoid Arthritis
Risk factors for serious side effects
LodineMorphine Sulfate
    Coming soon.
    • Current use of medicine that affects liver enzyme CYP 3A4
    • Age 65 or greater
    • Higher dose
    • People with not enough thyroid hormones
    • History of lung problems
    Detailed Ms Contin (morphine sulfate) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Food
    LodineMorphine Sulfate
    No food related info.
    • Take it with food to lower the chance of an upset stomach.
    Pain
    LodineMorphine Sulfate
    No pain related info.
    • Good for chronic pain that requires around-the-clock relief.
    • Doesn't work for as-needed or quick pain relief.
    Sleep
    LodineMorphine Sulfate
    No sleep related info.
    • Dizziness and drowsiness is common, but your body may adjust.
    Upsides and benefits
    LodineMorphine Sulfate
    Coming soon
    • Provides longer relieve for moderate to severe pain to improve quality of life.
    • Good for chronic pain that requires around-the-clock relief.
    • Might have fewer side effects than other opioid pain relievers.
    Downsides and risks
    LodineMorphine Sulfate
    Coming soon
    • Doesn't work for as-needed or quick pain relief.
    • Dizziness and drowsiness is common, but your body may adjust.
    • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Ms Contin (Morphine Sulfate) if you need.
    • Long term use will likely cause physical dependence.
    • Must be weaned slowly off the medicine after use longer than 2 weeks.
    Tips from our pharmacists for people taking the medication
    LodineMorphine Sulfate
    Coming soon
    • Opioid pain medicine that provides longer pain relief—up to 12 hours.
    • Works best when taken regularly instead of as-needed.
    • Especially useful for people with chronic pain problems.
    • May not be the best choice for people who have never taken an opioid pain medicine because it lasts so long.
    • Swallow it whole. Don't crush, chew, or split the medicine.
    • Can make you dizzy or drowsy.
    • Avoid activities that need you to be fully alert until you know how it affects you.
    • Take it with food to lower the chance of an upset stomach.
    • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and taking laxatives can help.
    • Talk to your doctor if it doesn't help enough for your pain, or if the side effects are really bad.
    Learn more
    More about LodineSide effectsReviews & ratingsFDA package insert
    Have you used Lodine (etodolac)?
    Worth itNot sureNot worth it
    More about Morphine SulfateSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Ms Contin (morphine sulfate)?
    Worth itNot sureNot worth it