Compare Lodine vs. Morphine sulfate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lodine
(Etodolac)

Ms Contin
(Morphine Sulfate)

Coming soon.Treats severe pain. Ms Contin (Morphine Sulfate) provides good long-term pain control without the need to take medicine frequently, but watch out for constipation.
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Reviews & ratings
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Reviews for Ms Contin (Morphine Sulfate)
55%
+38% vs. Lodine (Etodolac)
43%
+26% vs. Lodine (Etodolac)
20%
3% vs. Lodine (Etodolac)
Side effects
LodineMorphine sulfate

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »

The Morphine sulfate FDA package insert doesn’t have numbers about how common side effects are.

More about Morphine sulfate side effects »
How it works
LodineMorphine sulfate
Coming soon.Ms Contin (Morphine Sulfate) is an opioid medicine that works in the brain to lower pain perception.
Type of medication
LodineMorphine sulfate
Coming soon.
Pain reliever
Opioid
Prescription only
Available as
LodineMorphine sulfate
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Oral solution
  • Liquid
  • Suppository
Used for (click to learn more)
LodineMorphine sulfate
  • Juvenile rheumatoid arthritis Osteoarthritis Pain Rheumatoid arthritis
Risk factors for serious side effects
LodineMorphine sulfate
Coming soon.
  • Current use of medicine that affects liver enzyme CYP 3A4
  • Age 65 or greater
  • Higher dose
  • People with not enough thyroid hormones
  • History of lung problems
  • Children age 18 and younger
  • Long-term use during pregnancy
  • Taking more than the prescribed dose
  • Long-term use
  • History of drug abuse
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 or greater
  • Age 65 years or older
Detailed Ms Contin (Morphine Sulfate) risks & warnings »
Pregnancy category
LodineMorphine sulfate
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Can make you dizzy or drowsy.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
LodineMorphine sulfate
Coming soon.
  • Provides longer relieve for moderate to severe pain to improve quality of life.
  • Good for chronic pain that requires around-the-clock relief.
  • Might have fewer side effects than other opioid pain relievers.
Downsides and risks
LodineMorphine sulfate
Coming soon.
  • Doesn't work for as-needed or quick pain relief.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Ms Contin (Morphine Sulfate) if you need.
  • Long term use will likely cause physical dependence.
  • Must be weaned slowly off the medicine after use longer than 2 weeks.
Tips from our pharmacists for people taking the medication
LodineMorphine sulfate
Coming soon.
  • Opioid pain medicine that provides longer pain relief—up to 12 hours.
  • Works best when taken regularly instead of as-needed.
  • Especially useful for people with chronic pain problems.
  • May not be the best choice for people who have never taken an opioid pain medicine because it lasts so long.
  • Swallow it whole. Don't crush, chew, or split the medicine.
  • Can make you dizzy or drowsy.
  • Avoid activities that need you to be fully alert until you know how it affects you.
  • Take it with food to lower the chance of an upset stomach.
  • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and taking laxatives can help.
  • Talk to your doctor if it doesn't help enough for your pain, or if the side effects are really bad.
Learn more
More about LodineSide effectsReviews & ratingsFDA package insert
More about Morphine sulfateSide effectsReviews & ratingsAlternativesFDA package insert