Compare Lodine vs. Tramadol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lodine
(Etodolac)

Ultram
(Tramadol)

Coming soon.Treats moderate to severe pain. Ultram (Tramadol) works well to treat severe pain and mood changes. Although it's a little weaker than other opioids, it can still be addictive.
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Reviews & ratings
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Reviews for Ultram (Tramadol)
61%
+44% vs. Lodine (Etodolac)
39%
+22% vs. Lodine (Etodolac)
16%
+1% vs. Lodine (Etodolac)
Side effects
LodineTramadol

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »
  • Dizziness (not vertigo) 21%
  • Flushing 12%
  • Itching 11%
  • Dry mouth 10%
  • Dizziness 9%
  • Sleep difficulty 8%
  • Positional low blood pressure 3%
More Tramadol side effects »
How it works
LodineTramadol
Coming soon.Ultram (Tramadol) is an atypical opioid pain reliever. Researchers don't know exactly how it works, but it alters certain brain chemicals to lower pain perception and improve mood.
Type of medication
LodineTramadol
Coming soon.
Pain reliever
Opioid
Prescription only
Available as
LodineTramadol
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Extended release capsule
  • Dissolving tablet
Used for (click to learn more)
LodineTramadol
  • Juvenile rheumatoid arthritis Osteoarthritis Pain Rheumatoid arthritis
Risk factors for serious side effects
LodineTramadol
Coming soon.
  • Higher dose
  • Using other medicines that can cause seizures
  • History of seizures
  • Alcoholism
  • Eating disorders
  • Brain infections
  • Suicidal or at risk
  • Taking other medications that affect serotonin
  • Drug or alcohol abuse
  • Using other medications that affect serotonin
  • History of allergic reactions to codeine or other opioid pain relievers
  • Phenylalanine sensitivity
  • Stopping Ultram (Tramadol) suddenly
  • Taking more than the prescribed dose
  • Taking with alcohol or drugs
  • Taking with alcohol or drugs
    Detailed Ultram (Tramadol) risks & warnings »
    Pregnancy category
    LodineTramadol
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.
    • Serious side effects may include drug abuse, dependence, slowed breathing rate (respiratory depression), and death. Don't take more than your doctor prescribes or take with alcohol, illegal drugs, or other opioid pain relievers.
    Food
    No specific food-related info.
    • Take Ultram (Tramadol) with food to avoid an upset stomach.
    Kidneys and liver
    No specific kidneys and liver-related info.
    • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.
    • Can make you dizzy or drowsy, so avoid activities that need you to be fully alert until you know how this medicine affects you.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    LodineTramadol
    Coming soon.
    • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
    • Compared to typical opioids, it provides unique pain relief and effects on your mood when taken regularly.
    • Has a lower chance of causing breathing problems compared to other typical opioids.
    • Doesn't cause as much constipation as other opioid pain medicines. Staying hydrated and taking laxatives can help treat this side effect.
    Downsides and risks
    LodineTramadol
    Coming soon.
    • Some people think it's weaker than other opioid pain medications. It can also cause more upset stomach.
    • Like other opioid pain relievers, Tramadol has a high risk of addiction, abuse, misuse, overdose, and death. It should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
    • It isn't used for short-term, as-needed pain relief.
    • It's a controlled substance regulated by the federal government. This means that your use of Ultram (Tramadol) will be tracked to prevent potential prescription abuse.
    • To get Ultram (Tramadol) in the pharmacy, you'll need to bring in a paper prescription directly from your doctor.
    Tips from our pharmacists for people taking the medication
    LodineTramadol
    Coming soon.
    • Starts working in one hour and works best if you take it regularly.
    • Can make you dizzy or drowsy, so avoid activities that need you to be fully alert until you know how this medicine affects you.
    • Take Ultram (Tramadol) with food to avoid an upset stomach.
    • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
    • Swallow the extended-release tablets whole. They're designed to release the drug slowly and breaking, crushing, or chewing them could cause a serious overdose.
    Learn more
    More about LodineSide effectsReviews & ratingsFDA package insert
    More about TramadolSide effectsReviews & ratingsAlternativesFDA package insert