Compare Lodine vs. Tramadol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lodine
(etodolac)

Ultram
(tramadol)

Coming soon.Treats moderate to severe pain. Ultram (tramadol) works well for pain. Although it's a little weaker than other opioids, it can still be addictive.
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Prices and coupon for 60 (300mg) capsules of etodolac
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Prices and coupon for 120 (50mg) tablets of tramadol
Reviews & ratings
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Have you used Lodine (etodolac)?
Worth itNot sureNot worth it
Reviews for Ultram (tramadol)
61%
+31% better vs. Lodine (etodolac)
40%
+20% better vs. Lodine (etodolac)
16%
-6% worse vs. Lodine (etodolac)
642 reviews
Have you used Ultram (tramadol)?
Worth itNot sureNot worth it
Side effects
LodineTramadol

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »
  • Dizziness 26%
  • Constipation 24%
  • Nausea 24%
  • Headache 18%
  • Sleepiness 16%
  • Vomiting 9%
  • Itching 8%
  • Cns stimulation 7%
  • Muscle weakness 6%
  • Sweating 6%
More Tramadol side effects »
How it works
LodineTramadol
Coming soon.Ultram (tramadol) is an opioid pain reliever. Researchers don't know exactly how it works, but it alters certain brain chemicals to lower pain perception and improve mood.
Type of medication
LodineTramadol
Prescription only
Available as
LodineTramadol
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Extended release capsule
  • Dissolving tablet
Used for
LodineTramadol
  • Juvenile Rheumatoid Arthritis Osteoarthritis Pain Rheumatoid Arthritis
Risk factors for serious side effects
LodineTramadol
Coming soon.
    • Pregnancy
    • Age 65 or greater
    • Overdose
    • Using alcohol, benzodiazepines or other medicines that slow breathing
    • Taking more than the prescribed dose
    • Taking with alcohol or benzodiazepines
    • Stopping Ultram (tramadol) suddenly
    • Children can reach medication
    Detailed Ultram (tramadol) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    LodineTramadol
    No interactions related info.
    • Ultram (tramadol) can interact with your other medicines, which can change how it affects your pain. Stopping these medicines while taking Ultram (tramadol) can make you more likely to have serious, life threatening side effects. Make sure your doctor and pharmacist know all the medicines you're taking, and let them know of any changes.
    Food
    LodineTramadol
    No food related info.
    • Take Ultram (tramadol) with food to avoid an upset stomach.
    Kidneys and liver
    LodineTramadol
    No kidneys and liver related info.
    • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
    Pain
    LodineTramadol
    No pain related info.
    • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
    • The extended release version of Ultram (tramadol) should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
    • Ultram (tramadol) can interact with your other medicines, which can change how it affects your pain. Stopping these medicines while taking Ultram (tramadol) can make you more likely to have serious, life threatening side effects. Make sure your doctor and pharmacist know all the medicines you're taking, and let them know of any changes.
    Upsides and benefits
    LodineTramadol
    Coming soon
    • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
    • Compared to typical opioids, it provides unique pain relief and effects on your mood when taken regularly.
    • Has a lower chance of causing breathing problems compared to other typical opioids.
    • Doesn't cause as much constipation as other opioid pain medicines. Staying hydrated and taking laxatives can help treat this side effect.
    Downsides and risks
    LodineTramadol
    Coming soon
    • Some people think it's weaker than other opioid pain medications. It can also cause more upset stomach.
    • Like other opioid pain relievers, Ultram (tramadol) has a high risk of addiction, abuse, misuse, overdose, and death.
    • The extended release version of Ultram (tramadol) should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
    • It's a controlled substance regulated by the federal government. This means that your use of Ultram (tramadol) will be tracked to prevent potential prescription abuse.
    • Like all opioids, don't use when pregnant, since the baby can become dependent on it and have withdrawal symptoms after birth.
    Tips from our pharmacists for people taking the medication
    LodineTramadol
    Coming soon
    • Starts working in one hour and works best if you take it regularly.
    • Can make you dizzy or drowsy, so avoid activities that need you to be fully alert until you know how this medicine affects you.
    • Take Ultram (tramadol) with food to avoid an upset stomach.
    • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
    • Swallow the extended-release tablets whole. They're designed to release the drug slowly and breaking, crushing, or chewing them could cause a serious overdose.
    • Take the extended-release tablets exactly as your doctor and pharmacist tell you. If you forget, take it as soon as you remember. Don't take extra medicine to make up for a missed dose.
    Learn more
    More about LodineSide effectsReviews & ratingsFDA package insert
    Have you used Lodine (etodolac)?
    Worth itNot sureNot worth it
    More about TramadolSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Ultram (tramadol)?
    Worth itNot sureNot worth it