Compare Lodine vs. Voltaren

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lodine
(Etodolac)

Voltaren
(Diclofenac Sodium)

Coming soon.Relieves pain and inflammation. Voltaren (Diclofenac Sodium) works well for pain and causes less upset stomach than other NSAIDs.
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Reviews & ratings
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Reviews for Voltaren (Diclofenac Sodium)
73%
+56% vs. Lodine (Etodolac)
68%
+51% vs. Lodine (Etodolac)
9%
+8% vs. Lodine (Etodolac)
Side effects
LodineVoltaren

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »
  • Application site contact dermatitis 29%
  • Application site rash 29%
  • Dry skin (application site) 27%
  • Application site dry skin 15%
  • Application site rash 15%
  • Application site reaction 14%
  • Any side effect 14%
  • Application site exfoliation 11%
  • Application site pruritus 7%
  • Contact dermatitis (application site) 7%
More Voltaren side effects »
How it works
LodineVoltaren
Coming soon.Voltaren (Diclofenac Sodium) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.
Type of medication
LodineVoltaren
Coming soon.
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Available as
LodineVoltaren
  • Pill
  • Extended release
  • Extended release
  • Cream, gel, or ointment
  • Eye drops
Used for (click to learn more)
LodineVoltaren
  • Juvenile rheumatoid arthritis Osteoarthritis Pain Rheumatoid arthritis
Risk factors for serious side effects
LodineVoltaren
Coming soon.
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Being overweight or obese
  • Smoking
  • History of stomach bleeding or ulcers
  • Age 65 years or older
  • Hemophilia
  • von Willebrand's disease
  • Low blood platelet count
  • Also taking an anticoagulant medication
  • Asthma
  • Rhinitis
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking diuretics
  • Taking ACE inhibitors or angiotensin receptor blockers (ARBs)
  • Age 65 or older
  • History of high blood pressure
  • Taking water pills (diuretics)
  • Late pregnancy (more than 30 weeks)
Detailed Voltaren (Diclofenac Sodium) risks & warnings »
Pregnancy category
LodineVoltaren
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.
  • If taking Voltaren (Diclofenac Sodium) by mouth, take it with a meal or a snack to prevent an upset stomach.
Kidneys and liver
No specific kidneys and liver-related info.
  • Can lower kidney function or cause permanent kidney damage. These problems are more likely the longer you take it.
  • Can affect your kidneys' ability to work as well.
  • Voltaren (Diclofenac Sodium), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk of kidney problems. It's important to get lab tests to check your kidney function periodically if you use Voltaren (Diclofenac Sodium) for long periods of time.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
LodineVoltaren
Coming soon.
  • Works well to relieve pain and inflammation from osteoarthritis and rheumatoid arthritis.
  • Good for muscle aches and pains.
  • May treat arthritis pain better than other similar medicines (NSAIDs).
  • Can cause less upset stomach than other NSAIDs like ibuprofen (Advil).
  • It's also available as a gel that you put on your skin. If it's hard for you to swallow pills, this could be a good option.
  • If you're only using the gel, you won't have the same side effects that you would while taking Voltaren (Diclofenac Sodium) by mouth.
Downsides and risks
LodineVoltaren
Coming soon.
  • Can cause serious stomach problems like inflammation, ulcers, and bleeding. The chances that a stomach problem will occur is worse the longer you take this medication, but it can happen at any time while taking it.
  • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
  • Can lower kidney function or cause permanent kidney damage. These problems are more likely the longer you take it.
Tips from our pharmacists for people taking the medication
LodineVoltaren
Coming soon.
  • If taking Voltaren (Diclofenac Sodium) by mouth, take it with a meal or a snack to prevent an upset stomach.
  • Can cause stomach ulcers, especially if taking it by mouth often.
  • Can make you bruise or bleed more easily. You shouldn't take any other 'blood thinner' medications unless your doctor tells you it's safe.
  • Don't use it the first two weeks after a heart surgery.
  • Can affect your kidneys' ability to work as well.
  • If using the skin (topical) gel, use the dosing card it comes with to make sure you measure the correct dose. You also won't have many of the same side effects that you would if taking Voltaren (Diclofenac Sodium) by mouth.
Learn more
More about LodineSide effectsReviews & ratingsFDA package insert
More about VoltarenSide effectsReviews & ratingsAlternativesFDA package insert