Compare Lopressor vs. Bisoprolol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(metoprolol tartrate)

Zebeta
(bisoprolol)

Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.Lowers blood pressure. Zebeta (Bisoprolol) is usually given to people who have taken other blood pressure meds unsuccessfully or have recently had significant heart problems.
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Coupons for Lopressor
Best available price for 60 (25mg) tablets of lopressor
Coupons for Bisoprolol
Best available price for 30 (5mg) tablets of bisoprolol
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Lopressor
Reviews for Lopressor
62%
of people (All ages) say Lopressor is worth it
47%
say it works well
15%
say it's a big hassle
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Reviews for Bisoprolol
67%
-5% worse vs. Lopressor
61%
-14% worse vs. Lopressor
28%
+13% better vs. Lopressor
Have you used Zebeta (bisoprolol)?
Worth itNot sureNot worth it
Side effects
LopressorBisoprolol
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »

We haven’t found good data for Bisoprolol side effects.

FDA side effect reports for Bisoprolol »
How it works
LopressorBisoprolol
Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Zebeta (Bisoprolol) is a selective beta blocker that works specifically on the heart. It lowers blood pressure by slowing down the heart and making it work less to pump.
Type of medication
LopressorBisoprolol
Prescription onlyPrescription only
Available as
LopressorBisoprolol
  • Pill
  • Pill
Used for
LopressorBisoprolol
Risk factors for serious side effects
LopressorBisoprolol
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
  • Diabetes
  • Coronary artery disease
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Zebeta (bisoprolol) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
LopressorBisoprolol
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
No food related info.
Pain
LopressorBisoprolol
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
No pain related info.
Upsides and benefits
LopressorBisoprolol
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
  • Good for protecting the heart and lowering blood pressure if you've had a heart attack.
  • Available in a generic version.
  • Also comes in combination with other medications to lower blood pressure.
Downsides and risks
LopressorBisoprolol
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • This isn't a first choice medication to lower blood pressure.
  • You can't stop taking it suddenly, or else you're more likely to have a heart attack or other problems with your heart.
Tips from our pharmacists for people taking the medication
LopressorBisoprolol
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
  • Zebeta (Bisoprolol) can make you feel dizzy the first few days you take it, so be careful driving and quickly standing up until you know how your body reacts to it.
  • Don't stop taking it suddenly without talking to your doctor.
  • If you have diabetes, Zebeta (Bisoprolol) can make it difficult to tell if your blood sugar is low.
  • Can cause headache, fatigue, and make you more likely to get colds or the flu.
Learn more
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
More about BisoprololSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zebeta (bisoprolol)?
Worth itNot sureNot worth it