Compare Lopressor vs. Bystolic

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(metoprolol tartrate)

Bystolic
(nebivolol)

Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.Lowers blood pressure and controls heart rate. Bystolic (Nebivolol) is a good blood pressure-lowering medicine for people with heart conditions, and has fewer side effects than other beta blockers, but it's expensive. You can't miss doses.
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Coupons for Lopressor
Best available price for 60 (25mg) tablets of lopressor
Coupons for Bystolic
Best available price for 30 (10mg) tablets of bystolic
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Lopressor
Reviews for Lopressor
62%
of people (All ages) say Lopressor is worth it
47%
say it works well
15%
say it's a big hassle
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Reviews for Bystolic
53%
+9% better vs. Lopressor
49%
-2% worse vs. Lopressor
18%
+3% better vs. Lopressor
154 reviews
Have you used Bystolic (nebivolol)?
Worth itNot sureNot worth it
Side effects
LopressorBystolic
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
  • Headache 3%
  • Fatigue 1%
  • Nausea 3%
More Bystolic side effects »
How it works
LopressorBystolic
Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Bystolic (Nebivolol) is a selective beta blocker that works specifically on the heart. It lowers blood pressure by slowing down the heart and making it work less to pump.
Type of medication
LopressorBystolic
Prescription onlyPrescription only
Available as
LopressorBystolic
  • Pill
  • Pill
Used for
LopressorBystolic
Risk factors for serious side effects
LopressorBystolic
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
  • Sudden discontinuation of medicine
  • History of asthma
  • History of diabetes
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Bystolic (nebivolol) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
LopressorBystolic
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
No food related info.
Pain
LopressorBystolic
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
No pain related info.
Upsides and benefits
LopressorBystolic
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
  • Controls your heart rate to reduce work for your heart.
  • A first-line treatment for heart failure and heart attack.
  • Helps to lower blood pressure if you can't use first-choice treatments or need additional blood pressure control.
  • Many beta blockers can worsen asthma or cause headaches, but Bystolic usually doesn't because it targets the heart more specifically and causes fewer side effects.
Downsides and risks
LopressorBystolic
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not available in less expensive generic form.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Bystolic suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
LopressorBystolic
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
  • Can cause headache, dizziness, or feeling short of breath in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Don't stop taking this medicine suddenly.
Learn more
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
More about BystolicSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Bystolic (nebivolol)?
Worth itNot sureNot worth it