Compare Lopressor vs. Catapres

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(Metoprolol Tartrate)

Catapres
(Clonidine)

Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.99103139013453Lopressor
Reviews for Lopressor (Metoprolol Tartrate)
61%
of people say Lopressor (Metoprolol Tartrate) is worth it
46%
say it works well
15%
say it's a big hassle
Reviews for Catapres (Clonidine)
42%
19% vs. Lopressor (Metoprolol Tartrate)
33%
13% vs. Lopressor (Metoprolol Tartrate)
34%
19% vs. Lopressor (Metoprolol Tartrate)
Side effects
LopressorCatapres
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • First-degree heart block 3%
More Lopressor side effects »

The Catapres FDA package insert doesn’t have numbers about how common side effects are.

More about Catapres side effects »
How it works
LopressorCatapres
Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.
Type of medication
LopressorCatapres
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Alpha agonist
Prescription only
Available as
LopressorCatapres
  • Pill
  • Pill
  • Extended release
  • Patch
Used for (click to learn more)
LopressorCatapres
Risk factors for serious side effects
LopressorCatapres
  • Diabetes
    • Coronary artery disease
    • Heart failure
    • Major surgery requiring anesthesia
    • History of asthma
    Detailed Lopressor (Metoprolol Tartrate) risks & warnings »
    • Sudden discontinuation of medicine
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 years or older
    • Using other medicine(s) that slows the heart
    Detailed Catapres (Clonidine) risks & warnings »
    Pregnancy category
    LopressorCatapres
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Take it with food.
    No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    LopressorCatapres
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
    • Available in a weekly patch for people that aren't good at taking medicine by mouth.
    • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
    • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
    Downsides and risks
    LopressorCatapres
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • Can hide symptoms of low blood sugar if you're diabetic.
    • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
    • The pill form can make some people sleepy, dizzy, and have dry mouth.
    • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    Tips from our pharmacists for people taking the medication
    LopressorCatapres
    • Take it with food.
    • Can cause dizziness in the first few days.
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Don't stop taking this medicine suddenly.
    • Usually taken together with other medicines for better blood pressure control.
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    • If side effects don't go away, talk to your doctor about alternatives.
    • The weekly patch form can have fewer side effects.
    • Extended release tablet also used to treat ADHD.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Don't stop taking this medicine suddenly.
    Learn more
    More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
    More about CatapresSide effectsReviews & ratingsAlternativesFDA package insert