Compare Lopressor vs. Hyzaar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lopressor
(Metoprolol Tartrate)

Hyzaar
(Losartan / Hydrochlorothiazide)

Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure. Removes extra water from your body. Hyzaar (Losartan / Hydrochlorothiazide) is a good combination blood pressure-lowering medicine to try if your blood pressure is very high.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.99103139013453Lopressor
Reviews for Lopressor (Metoprolol Tartrate)
61%
of people say Lopressor (Metoprolol Tartrate) is worth it
46%
say it works well
15%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
LopressorHyzaar
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • First-degree heart block 3%
More Lopressor side effects »
  • Dizziness 3%
  • Back pain 1%
  • Cough 1%
  • Upper respiratory infection 1%
More Hyzaar side effects »
How it works
LopressorHyzaar
Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Hyzaar (Losartan / Hydrochlorothiazide) is a combination medicine that lowers your blood pressure. Hydrochlorothiazide is a diuretic that removes extra water from your body. Losartan is an angiotensin receptor blocker (ARB) that relaxes your blood vessels to lower you blood pressure and allow more blood and oxygen to get to your heart and other organs.
Type of medication
LopressorHyzaar
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Angiotensin receptor blocker
Diuretic
Prescription only
Available as
LopressorHyzaar
  • Pill
  • Pill
Used for (click to learn more)
LopressorHyzaar
Risk factors for serious side effects
LopressorHyzaar
  • Diabetes
    • Coronary artery disease
    • Heart failure
    • Major surgery requiring anesthesia
    • History of asthma
    Detailed Lopressor (Metoprolol Tartrate) risks & warnings »
    • Women of childbearing age
    • History of kidney problems
    • African descent
    • Current kidney problems
    • Medicine that affects potassium
    • Use of salt substitute
    • History of sulfa allergies
    • History of gout
    • Current kidney problems
    Detailed Hyzaar (Losartan / Hydrochlorothiazide) risks & warnings »
    Pregnancy category
    LopressorHyzaar
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Take it with food.
    No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.
    • Requires a yearly blood test to see how the medicine is affecting your electrolytes and kidneys.
    • Won't work as well if you have severe kidney problems.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Get your blood pressure, potassium, and kidney function checked 1 week after starting the medicine, then routinely after.
    • Requires routine blood tests to check kidney function.
    • Hyzaar (Losartan / Hydrochlorothiazide) has a risk of making your kidneys not work as well. It is important to get blood work done to check your kidney function before starting Hyzaar (Losartan / Hydrochlorothiazide) and at least annually after.
    • Hyzaar (Losartan / Hydrochlorothiazide) can affect the potassium level in your body. Too much potassium can cause heart problems and too little potassium can cause muscle problems. Baseline and routine lab tests are needed to measure your potassium and kidney function.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    LopressorHyzaar
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    • Lowers the risk of heart attack and stroke.
    • A first-choice treatment for severe high blood pressure, combining the benefits of two blood pressure-lowering medicines with a single pill.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Helpful in getting rid of extra fluids if you have issues with fluid balance (like in congestive heart failure).
    • Most people have few side effects.
    Downsides and risks
    LopressorHyzaar
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • Can hide symptoms of low blood sugar if you're diabetic.
    • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Will make you urinate more often.
    • Requires a yearly blood test to see how the medicine is affecting your electrolytes and kidneys.
    • Not safe to use if you're pregnant.
    • Needs dose adjustment if you have liver problems.
    • Your skin will be more sensitive to the sun while taking this.
    • Won't work as well if you have severe kidney problems.
    • Shouldn't take if you have a sulfa allergy.
    Tips from our pharmacists for people taking the medication
    LopressorHyzaar
    • Take it with food.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Don't stop taking this medicine suddenly.
    • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
    • Can cause dizziness in the first few days.
    • Get your blood pressure, potassium, and kidney function checked 1 week after starting the medicine, then routinely after.
    • Tell your doctor about any dizziness or muscle weakness that doesn't go away.
    • Get immediate medical help if you notice any swelling, especially around your head and neck.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    • Can cause dizziness in the first few days.
    Learn more
    More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
    More about HyzaarSide effectsReviews & ratingsAlternativesFDA package insert