Compare Lopressor vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zestril (lisinopril)

Prescription only
Lowers blood pressure and controls heart rate.

Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.

3.7/ 5 average rating with 464 reviewsforLopressor
Lowers blood pressure.

Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

3.8/ 5 average rating with 687 reviewsforLisinopril
Upsides
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
Downsides
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
Used for
Dosage forms
  • Pill
  • Pill
  • Liquid
Price
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Reviews
464 reviews so far
62%
saidit'sworth it
47%
saiditworked well
15%
saidit'sa big hassle

Have you used Lopressor (metoprolol tartrate)?

Leave a review
687 reviews so far
61%
saidit'sworth it
51%
saiditworked well
14%
saidit'sa big hassle

Have you used Zestril (lisinopril)?

Leave a review
Side effects
7possible side effects
  • Tiredness
    10%
  • Dizziness
    10%
  • Depression
    5%
  • Diarrhea
    5%
  • Itching or skin rash
    5%
  • Shortness of breath
    3%
  • Slowed heart rate
    3%
See more detailed side effects
1possible side effects
  • Low blood pressure
    5%
See more detailed side effects
Risks and risk factors
  • Heart problems
    • Suddenly stopping Lopressor (metoprolol tartrate)
    • Coronary artery disease
  • Masked symptoms of low blood sugar
    • Diabetes
  • Masked symptoms of overactive thyroid
  • Increased symptoms of heart failure
    • Heart failure
  • Increased risks during surgery
    • Major surgery requiring anesthesia
  • Breathing problems
    • Asthma
    • COPD
See more detailed risks and warnings
  • Harm to fetus
    • Women of childbearing age
  • Cough
  • Swelling of face and head
    • African descent
  • High potassium
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
  • Worsening kidney problems
    • History of kidney problems
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
See more detailed risks and warnings